ZG20_XENLA
ID ZG20_XENLA Reviewed; 675 AA.
AC P18714;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 2.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Gastrula zinc finger protein xFG20-1;
DE AltName: Full=XlCGF20.1;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8001572; DOI=10.1111/j.1432-1033.1994.tb20082.x;
RA Schaefer U., Rausch O., Bouwmeester T., Pieler T.;
RT "Sequence-specific recognition of a repetitive DNA element by a C2H2 zinc-
RT finger protein in Xenopus.";
RL Eur. J. Biochem. 226:567-576(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 85-613.
RX PubMed=2509712; DOI=10.1016/0022-2836(89)90155-1;
RA Nietfeld W., El-Baradi T., Mentzel H., Pieler T., Koester M., Poeting A.,
RA Knoechel W.;
RT "Second-order repeats in Xenopus laevis finger proteins.";
RL J. Mol. Biol. 208:639-659(1989).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; X82643; CAA57965.1; -; Genomic_DNA.
DR PIR; S51037; S51037.
DR AlphaFoldDB; P18714; -.
DR SMR; P18714; -.
DR Proteomes; UP000186698; Genome assembly.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF00096; zf-C2H2; 14.
DR SMART; SM00355; ZnF_C2H2; 18.
DR SUPFAM; SSF57667; SSF57667; 11.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 17.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 18.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..675
FT /note="Gastrula zinc finger protein xFG20-1"
FT /id="PRO_0000047788"
FT ZN_FING 62..84
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 90..112
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 118..140
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 146..168
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 174..196
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 202..224
FT /note="C2H2-type 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 257..279
FT /note="C2H2-type 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 286..308
FT /note="C2H2-type 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 344..366
FT /note="C2H2-type 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 373..395
FT /note="C2H2-type 10"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 424..446
FT /note="C2H2-type 11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 452..474
FT /note="C2H2-type 12"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 480..501
FT /note="C2H2-type 13"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 507..529
FT /note="C2H2-type 14"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 535..557
FT /note="C2H2-type 15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 563..585
FT /note="C2H2-type 16"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 591..613
FT /note="C2H2-type 17"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 619..642
FT /note="C2H2-type 18"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT REGION 302..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 675 AA; 77116 MW; 033094852C1FCF39 CRC64;
MFCKEEEPYE FPENTFGTNE LLPNYQQNCT DGEAISDTKS DLAYLEVEIT DAHEESNTDK
PFTCTECGKT FTRKPNYESH IRAHKGEKPF SCMVCDKAFA WKSNLLVHYS VHSGEKPFSC
TECDKTFSNK AQLEKHLRVH TGEKPYSCEQ CGKSFAHKCV LDSHQRTHTG DKPFSCTECG
KKFSQRGNLH KHLKTHKLDQ PHLCAECGKT FSFKSTLLEH QKIHSEIRPL SEFGKTFSDA
HNLLKHQSTF TEEQKPFPCT ECGEIFSNEH ELLTHQSTHT EEQKPFPCTK CWGIFSNEHE
LRTHQSTHTE GQKSLPSTES GGTFSNEHEL LTHQSTHTEE QKHLPCTECG GTFTNEQELL
AHQSTHTEEQ KPLPCTECGE IFSDEHELLT HQSTHTSPST EFGVQTTEDN HQSPSKDHTG
EKPFSCSECG KSFFYKSVLK DHLVVHTGKK PYHCIECGRS YTHQSSLKSH QRTHTGVKAF
SCNLCDKLSI ISKLRLHYRV HSGEKPYPCT ECDKTFTKKE QLESHYKVHT GEKPYPCQQC
GKSFSHKSVL KLHLRTHTGD KPFSCTECGK TFTRKPNYES HLTTHTGKKP FSCTECGKEF
AWKRNLEAHY KMHTGEKPFT CTECGKTFTW KSNLRSHYTT VHGISPIQYA CTEEDVNVIK
TEEGDSFSYM VTLEN
