ZG48_XENLA
ID ZG48_XENLA Reviewed; 647 AA.
AC P18723;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1990, sequence version 1.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=Gastrula zinc finger protein XlCGF48.2;
DE Flags: Fragment;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 1-339.
RX PubMed=2503827; DOI=10.1073/pnas.86.16.6097;
RA Knoechel W., Poeting A., Koester M., el Baradi T., Nietfeld W.,
RA Bouwmeester T., Pieler T.;
RT "Evolutionary conserved modules associated with zinc fingers in Xenopus
RT laevis.";
RL Proc. Natl. Acad. Sci. U.S.A. 86:6097-6100(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 312-647.
RX PubMed=2509712; DOI=10.1016/0022-2836(89)90155-1;
RA Nietfeld W., El-Baradi T., Mentzel H., Pieler T., Koester M., Poeting A.,
RA Knoechel W.;
RT "Second-order repeats in Xenopus laevis finger proteins.";
RL J. Mol. Biol. 208:639-659(1989).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; M25871; AAA50018.1; -; mRNA.
DR PIR; S06573; S06573.
DR AlphaFoldDB; P18723; -.
DR SMR; P18723; -.
DR MaxQB; P18723; -.
DR Proteomes; UP000186698; Genome assembly.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF00096; zf-C2H2; 10.
DR SMART; SM00355; ZnF_C2H2; 12.
DR SUPFAM; SSF57667; SSF57667; 7.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 12.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 12.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..>647
FT /note="Gastrula zinc finger protein XlCGF48.2"
FT /id="PRO_0000047796"
FT ZN_FING 317..339
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 345..367
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 373..395
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 401..423
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 429..451
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 457..479
FT /note="C2H2-type 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 485..507
FT /note="C2H2-type 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 513..535
FT /note="C2H2-type 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 541..563
FT /note="C2H2-type 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 569..591
FT /note="C2H2-type 10"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 597..619
FT /note="C2H2-type 11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 625..647
FT /note="C2H2-type 12"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT NON_TER 647
SQ SEQUENCE 647 AA; 73054 MW; 7405D10D6C2BA007 CRC64;
MMSEEASGTV MGNKERIVTL TLEMIYLLTG EHYIPRKKSD DGGALHAPGS VIQKENNKND
KKILELMSNI IQLLTGEEWG CLKTNTISHG ETKKENPQQL YLPDCDYEDK ADININLNAT
VCFDNESNTN VDKGANRWEA RNVPKSEFLP EEQPCAANSI KEESELCKAE YRPDCSFNPL
GKQIQGTDTP TANVGSSMNS SLSDNYLLKT IKEEPDSCEE EKLSDYKIIT VSEPVAEDQN
PAPSCSQNNR SLPNYVSNTI KEEPYDEEHF SDYRIITVTD PTQVAGTSPH STENGEYDSS
MAACTSQLSK SALNVMFNCN VCHTAFNNKS NLVRHQRIHT GEKPFSCSEC GKCFRQSSQL
FLHRRNHTGE KPFSCSECGK CFKWRSLLIK HHKTHTGDKS FTCADCGKCF KKFSRLTEHR
KCHTGEEPFV CSECGKSFAQ SPQLDLHMRI HTGEKPFSCS DCGKCFTQRA DLNVHRRTHT
GEKPFTCSVC GKGFTRRTQL NIHNRIHTGE NTFTCPECGK CFTQHSHLLA HQKGHMGKKP
FCCSECGKRF RQSTQLYLHQ KAHAGEKPFT CAECGQWFKL YSILVEHQKC HTGEKPFSCS
ECGKCFKRHT LLTEHQRIHT GENTFSCSVC GKCFTRHSHL TAHEKIH