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ZG48_XENLA
ID   ZG48_XENLA              Reviewed;         647 AA.
AC   P18723;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Gastrula zinc finger protein XlCGF48.2;
DE   Flags: Fragment;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 1-339.
RX   PubMed=2503827; DOI=10.1073/pnas.86.16.6097;
RA   Knoechel W., Poeting A., Koester M., el Baradi T., Nietfeld W.,
RA   Bouwmeester T., Pieler T.;
RT   "Evolutionary conserved modules associated with zinc fingers in Xenopus
RT   laevis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:6097-6100(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 312-647.
RX   PubMed=2509712; DOI=10.1016/0022-2836(89)90155-1;
RA   Nietfeld W., El-Baradi T., Mentzel H., Pieler T., Koester M., Poeting A.,
RA   Knoechel W.;
RT   "Second-order repeats in Xenopus laevis finger proteins.";
RL   J. Mol. Biol. 208:639-659(1989).
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; M25871; AAA50018.1; -; mRNA.
DR   PIR; S06573; S06573.
DR   AlphaFoldDB; P18723; -.
DR   SMR; P18723; -.
DR   MaxQB; P18723; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 10.
DR   SMART; SM00355; ZnF_C2H2; 12.
DR   SUPFAM; SSF57667; SSF57667; 7.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 12.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 12.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..>647
FT                   /note="Gastrula zinc finger protein XlCGF48.2"
FT                   /id="PRO_0000047796"
FT   ZN_FING         317..339
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         345..367
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         373..395
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         401..423
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         429..451
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         457..479
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         485..507
FT                   /note="C2H2-type 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         513..535
FT                   /note="C2H2-type 8"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         541..563
FT                   /note="C2H2-type 9"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         569..591
FT                   /note="C2H2-type 10"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         597..619
FT                   /note="C2H2-type 11"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         625..647
FT                   /note="C2H2-type 12"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   NON_TER         647
SQ   SEQUENCE   647 AA;  73054 MW;  7405D10D6C2BA007 CRC64;
     MMSEEASGTV MGNKERIVTL TLEMIYLLTG EHYIPRKKSD DGGALHAPGS VIQKENNKND
     KKILELMSNI IQLLTGEEWG CLKTNTISHG ETKKENPQQL YLPDCDYEDK ADININLNAT
     VCFDNESNTN VDKGANRWEA RNVPKSEFLP EEQPCAANSI KEESELCKAE YRPDCSFNPL
     GKQIQGTDTP TANVGSSMNS SLSDNYLLKT IKEEPDSCEE EKLSDYKIIT VSEPVAEDQN
     PAPSCSQNNR SLPNYVSNTI KEEPYDEEHF SDYRIITVTD PTQVAGTSPH STENGEYDSS
     MAACTSQLSK SALNVMFNCN VCHTAFNNKS NLVRHQRIHT GEKPFSCSEC GKCFRQSSQL
     FLHRRNHTGE KPFSCSECGK CFKWRSLLIK HHKTHTGDKS FTCADCGKCF KKFSRLTEHR
     KCHTGEEPFV CSECGKSFAQ SPQLDLHMRI HTGEKPFSCS DCGKCFTQRA DLNVHRRTHT
     GEKPFTCSVC GKGFTRRTQL NIHNRIHTGE NTFTCPECGK CFTQHSHLLA HQKGHMGKKP
     FCCSECGKRF RQSTQLYLHQ KAHAGEKPFT CAECGQWFKL YSILVEHQKC HTGEKPFSCS
     ECGKCFKRHT LLTEHQRIHT GENTFSCSVC GKCFTRHSHL TAHEKIH
 
 
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