ID   ZGPAT_DROAN             Reviewed;         511 AA.
AC   B3MPC0;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN   ORFNames=GF15731;
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14024-0371.13;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CH902620; EDV32239.1; -; Genomic_DNA.
DR   RefSeq; XP_001963018.1; XM_001962982.2.
DR   AlphaFoldDB; B3MPC0; -.
DR   SMR; B3MPC0; -.
DR   STRING; 7217.FBpp0118923; -.
DR   PRIDE; B3MPC0; -.
DR   EnsemblMetazoa; FBtr0120431; FBpp0118923; FBgn0092755.
DR   GeneID; 6498536; -.
DR   KEGG; dan:6498536; -.
DR   eggNOG; KOG2185; Eukaryota.
DR   HOGENOM; CLU_040504_1_0_1; -.
DR   InParanoid; B3MPC0; -.
DR   OMA; QYTRGIG; -.
DR   OrthoDB; 1238995at2759; -.
DR   PhylomeDB; B3MPC0; -.
DR   Proteomes; UP000007801; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR043560; ZGPAT.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR46297; PTHR46297; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..511
FT                   /note="Zinc finger CCCH-type with G patch domain-containing
FT                   protein"
FT                   /id="PRO_0000385200"
FT   DOMAIN          311..357
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   ZN_FING         157..180
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          254..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          409..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          478..511
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..280
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        478..495
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        496..511
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   511 AA;  58132 MW;  F353D50C4B53160D CRC64;
     MDEYEAQLLV VEQALENATD EHQRQELLAL KENLQELLSL TRGGTEDDAA TDDDSQNADN
     LDNELERLKS ELNDMEATGA SKSNENEVQQ LADLRTKYSS MVGEKCSAPH EHSWGAISYH
     NALICGVDDE VIINGDGALD ARLRVLFTNP THREMLPCSY YLEGECRFDE ARCRYSHGAL
     VTGSSIRKYN PPDFHKLSRS CPVLAQLPDR LWHRGRVLCV NFVEQVCRVR LDGQDHKERE
     RDFKFEELFP LTTDQEDELT SEDSSSVNDG SSDEEESDMD DLEAARRARM VELSLFTFKP
     TEKLGAWEEY TRGIGSKLME KMGYIHGTGL GSDGRGIVTP VSAQILPKGR SLDACMELRE
     AANGDKDYFS VERKLQRAQR RQKKANEKAY VRESQRTDVF SFLNSSVLGS DNKQQAEPEA
     KKAKANDLQQ HSTKTLNVET VRIADDIRRK QRDIAKVQQS LDRNTGDVQL QKRLQAQMHN
     QKQELATLQA QERSLSKEQQ TRKSKNKMFE F