ID   ZGPAT_DROER             Reviewed;         513 AA.
AC   B3N8L3;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN   ORFNames=GG10072;
OS   Drosophila erecta (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7220;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14021-0224.01;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CH954177; EDV58436.1; -; Genomic_DNA.
DR   RefSeq; XP_001969377.1; XM_001969341.2.
DR   AlphaFoldDB; B3N8L3; -.
DR   SMR; B3N8L3; -.
DR   STRING; 7220.FBpp0128618; -.
DR   EnsemblMetazoa; FBtr0130126; FBpp0128618; FBgn0102384.
DR   GeneID; 6541394; -.
DR   KEGG; der:6541394; -.
DR   eggNOG; KOG2185; Eukaryota.
DR   HOGENOM; CLU_040504_1_0_1; -.
DR   OMA; QYTRGIG; -.
DR   OrthoDB; 1238995at2759; -.
DR   PhylomeDB; B3N8L3; -.
DR   Proteomes; UP000008711; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR043560; ZGPAT.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR46297; PTHR46297; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Repressor; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..513
FT                   /note="Zinc finger CCCH-type with G patch domain-containing
FT                   protein"
FT                   /id="PRO_0000385201"
FT   DOMAIN          312..358
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   ZN_FING         155..178
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          252..282
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          478..513
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        478..497
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        498..513
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   513 AA;  58696 MW;  FE6FADC42C9D64AC CRC64;
     MEEYEAQLLV VEQALENAAD EAQRQDLLAL KNNLQELLAL TRDTEDGAPT DELPQQGDDL
     DDELQRLRSE LNDLEAAGSS QTALDEERQL ADLRTKYTAM VGEKCSAPHE HSWGTCYHNA
     LICGVDDEVV MSSEGVLDAR LRVLFTNPTH REMLPCSYYL EGECRFDETK CRFSHGALVT
     GSSIRKYNPP DFHKLCRSRP VFALLPDRLW HRGRVLCVNF VEQVCRVRLD GQDHKERERD
     FKFEELYPLT TDQEEDDELS SEESNSSMNN ESSDEAESDM DDLEEARRAR MVELSLFTFK
     PTERLGAWEE FTRGIGSKLM EKMGYIHGTG LGSDGRGIVT PVSAQILPQG RSLDACMELR
     EAANGDKDYF SVERKLKRAQ RRQRKADEKA YVRESQRVDV FTFLNDSVLA PGESSQQGEQ
     VAKKVKTNEL QQHSTKTLNV ETVRIADEIR RKQRDMAKVK QSLDRNSGDA QLQKRLQVQM
     QSHKQELATL QAQERSLSKE QQTRKSKNKM FEF