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ZGPAT_DROGR
ID   ZGPAT_DROGR             Reviewed;         508 AA.
AC   B4JCG4;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN   ORFNames=GH11061;
OS   Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Hawaiian Drosophila.
OX   NCBI_TaxID=7222;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15287-2541.00;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CH916368; EDW03118.1; -; Genomic_DNA.
DR   RefSeq; XP_001988251.1; XM_001988215.1.
DR   AlphaFoldDB; B4JCG4; -.
DR   SMR; B4JCG4; -.
DR   STRING; 7222.FBpp0144967; -.
DR   EnsemblMetazoa; FBtr0146475; FBpp0144967; FBgn0118542.
DR   GeneID; 6562604; -.
DR   KEGG; dgr:6562604; -.
DR   eggNOG; KOG2185; Eukaryota.
DR   HOGENOM; CLU_040504_1_0_1; -.
DR   InParanoid; B4JCG4; -.
DR   OMA; QYTRGIG; -.
DR   OrthoDB; 1238995at2759; -.
DR   PhylomeDB; B4JCG4; -.
DR   Proteomes; UP000001070; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR043560; ZGPAT.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR46297; PTHR46297; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..508
FT                   /note="Zinc finger CCCH-type with G patch domain-containing
FT                   protein"
FT                   /id="PRO_0000385202"
FT   DOMAIN          313..359
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   ZN_FING         158..181
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          258..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          486..508
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        263..279
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   508 AA;  57660 MW;  631AE495F787428F CRC64;
     MDEYEAQLLV VEQALLVTTD EQQREELSAL RTNLEELLAL TRSSETEATN NISTAQTNGD
     LDDELKRFQS ELNDLKEQEQ EETDTTDDKQ QLEELRAKYN ALLGEKCSAP HEHSWGALSY
     HNALICGVDD ELIIDGNGIL DVRLRVLFTN PTHREMLPCN YYLEGECRFD EIRCRFSHGA
     LVPGASIKEY NAPDFHKLAR NCPVLAKLQD RLWHRGRVLC VNFVEQQCRV RLDGQEHKER
     ERDFPFEELF PLIADEDDEL SSDSSESHST EDSDAANDSD MDDLEAARQA RMVELSLFTF
     KPTEKLGAWE QYTRGIGSKL MANMGYIHGT GLGSDGRGIV TPVSAQILPQ GRSLDACMEL
     REAANGDKNY FSVERKLKRA QRRQQAANEK AYARESKRTD VFAFLNGSVL GQAQNSTKTT
     KTSNLQQHSN KTLNVETVRI ADDIRRKQRD IAKVQQSLAR NATDAQLQKR LNGQLRAHQQ
     ELATLQAQES SLSKEQQTRK SKNKMFAF
 
 
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