ID   ZGPAT_DROMO             Reviewed;         509 AA.
AC   B4KH32;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN   ORFNames=GI17578;
OS   Drosophila mojavensis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15081-1352.22;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CH933807; EDW12243.1; -; Genomic_DNA.
DR   RefSeq; XP_002002801.1; XM_002002765.2.
DR   AlphaFoldDB; B4KH32; -.
DR   SMR; B4KH32; -.
DR   STRING; 7230.FBpp0166795; -.
DR   EnsemblMetazoa; FBtr0168303; FBpp0166795; FBgn0140322.
DR   GeneID; 6576816; -.
DR   KEGG; dmo:Dmoj_GI17578; -.
DR   eggNOG; KOG2185; Eukaryota.
DR   HOGENOM; CLU_040504_1_0_1; -.
DR   InParanoid; B4KH32; -.
DR   OMA; QYTRGIG; -.
DR   OrthoDB; 1238995at2759; -.
DR   PhylomeDB; B4KH32; -.
DR   Proteomes; UP000009192; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR043560; ZGPAT.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR46297; PTHR46297; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..509
FT                   /note="Zinc finger CCCH-type with G patch domain-containing
FT                   protein"
FT                   /id="PRO_0000385204"
FT   DOMAIN          310..356
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   ZN_FING         155..178
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          41..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          254..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          410..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..277
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   509 AA;  57974 MW;  0062C6D3C0C6BDB5 CRC64;
     MDEYEAQLLV VKQALLVTSD EQQRDELIAL QTNLEELLAL TRGSEPEATS DTKTPETSDN
     IDDELQRFQS ELIDLEHQQA DPGEDQQRLE ELRTKYNGLL GEKCSAPHEH SWGALSYHNA
     LICGVDDELI VDKNGILDVR LRVLFTNPTH REMLPCNYFL EGECRFDEVR CRYSHGALVP
     GSSIKDYKAP DFHRLARNCS VLAKLQDRLW HRGRVLCVNF VEQQCRVRLD GQEHKERERD
     FPFEELFPLV TAEDDDLTSE SEESNETDGS DAGNDSDMDD FEAARQARMV ELSLFTFKPT
     ERLGAWEQYT RGIGSKLMAN MGYIHGTGLG SDGRGIVTPV SAQILPQGRS LDACMELREA
     ANGDKDYFSV ERKLKRAQRR QEAANEKAYE RASKRTDVFA FLNTSVLGQG SQQTENANKK
     TKPNNLQQHS NKTLNVETVR IADDIRRKQR DIAKVQQSLA RNATDAQLQK RLNVQLQAQK
     QELATLQAQE TSLCKEQQTR KSKNKMFEF