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ZGPAT_DROPE
ID   ZGPAT_DROPE             Reviewed;         509 AA.
AC   B4G7U3;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN   ORFNames=GL18949;
OS   Drosophila persimilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7234;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSH-3 / Tucson 14011-0111.49;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CH479180; EDW28441.1; -; Genomic_DNA.
DR   RefSeq; XP_002014445.1; XM_002014409.1.
DR   AlphaFoldDB; B4G7U3; -.
DR   SMR; B4G7U3; -.
DR   STRING; 7234.FBpp0183056; -.
DR   EnsemblMetazoa; FBtr0184564; FBpp0183056; FBgn0156550.
DR   GeneID; 6589220; -.
DR   KEGG; dpe:6589220; -.
DR   eggNOG; KOG2185; Eukaryota.
DR   HOGENOM; CLU_040504_1_0_1; -.
DR   OMA; QYTRGIG; -.
DR   PhylomeDB; B4G7U3; -.
DR   Proteomes; UP000008744; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR043560; ZGPAT.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR46297; PTHR46297; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..509
FT                   /note="Zinc finger CCCH-type with G patch domain-containing
FT                   protein"
FT                   /id="PRO_0000385205"
FT   DOMAIN          310..356
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   ZN_FING         155..178
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          253..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          409..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   509 AA;  58161 MW;  EE8EC1FDF3F227AC CRC64;
     MDEYEAQLVA VEQALENTTD EQQREELSTL RTNLQELLAL TRETEADQTA EQGDILDDEL
     LRLKSELNEL EEAAANVGAT KNKDEEQQLK DLRAKYNALV GEKCSAPHEH SWGALSYHNA
     LICGVDDEVI INRNSELDVR LRVLYINPTH CEMLPCNYYL EGECRFDEIR CRYSHGALVP
     GASIKSYIPP DFPRLARNCP VLAKMPDRLW HRGRVLCANF VEQTCRVRLD GQDHKERERD
     FQFEELFPLI TEEEDGLTSE DSSSSPHDES SDEIDSDMDD LEAAHRSRMV ELSLFTFKPT
     EKLGAWEQYT RGIGSKLMEK MGYIHGTGLG SEGRGIVTPV SAQILPQGRS LDACMELREA
     ANGDQDYFSV ERKLKRAQRR QNKANEKAYA RETQRTDVFS FLNGSVLGGG ESRHQGDQAA
     KKAKTNDLQQ HSTKTLNVET VRVADDIRRK QRDIAKVKQS LDRNATDIQL QKRLHMQLQS
     QKQELATLQA HEHRLSKEQH TRKNKMFEF
 
 
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