ZGPAT_DROPE
ID ZGPAT_DROPE Reviewed; 509 AA.
AC B4G7U3;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN ORFNames=GL18949;
OS Drosophila persimilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7234;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSH-3 / Tucson 14011-0111.49;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR EMBL; CH479180; EDW28441.1; -; Genomic_DNA.
DR RefSeq; XP_002014445.1; XM_002014409.1.
DR AlphaFoldDB; B4G7U3; -.
DR SMR; B4G7U3; -.
DR STRING; 7234.FBpp0183056; -.
DR EnsemblMetazoa; FBtr0184564; FBpp0183056; FBgn0156550.
DR GeneID; 6589220; -.
DR KEGG; dpe:6589220; -.
DR eggNOG; KOG2185; Eukaryota.
DR HOGENOM; CLU_040504_1_0_1; -.
DR OMA; QYTRGIG; -.
DR PhylomeDB; B4G7U3; -.
DR Proteomes; UP000008744; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR043560; ZGPAT.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR46297; PTHR46297; 1.
DR Pfam; PF01585; G-patch; 1.
DR SMART; SM00443; G_patch; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repressor;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..509
FT /note="Zinc finger CCCH-type with G patch domain-containing
FT protein"
FT /id="PRO_0000385205"
FT DOMAIN 310..356
FT /note="G-patch"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT ZN_FING 155..178
FT /note="C3H1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 253..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 509 AA; 58161 MW; EE8EC1FDF3F227AC CRC64;
MDEYEAQLVA VEQALENTTD EQQREELSTL RTNLQELLAL TRETEADQTA EQGDILDDEL
LRLKSELNEL EEAAANVGAT KNKDEEQQLK DLRAKYNALV GEKCSAPHEH SWGALSYHNA
LICGVDDEVI INRNSELDVR LRVLYINPTH CEMLPCNYYL EGECRFDEIR CRYSHGALVP
GASIKSYIPP DFPRLARNCP VLAKMPDRLW HRGRVLCANF VEQTCRVRLD GQDHKERERD
FQFEELFPLI TEEEDGLTSE DSSSSPHDES SDEIDSDMDD LEAAHRSRMV ELSLFTFKPT
EKLGAWEQYT RGIGSKLMEK MGYIHGTGLG SEGRGIVTPV SAQILPQGRS LDACMELREA
ANGDQDYFSV ERKLKRAQRR QNKANEKAYA RETQRTDVFS FLNGSVLGGG ESRHQGDQAA
KKAKTNDLQQ HSTKTLNVET VRVADDIRRK QRDIAKVKQS LDRNATDIQL QKRLHMQLQS
QKQELATLQA HEHRLSKEQH TRKNKMFEF