ID   ZGPAT_DROSE             Reviewed;         513 AA.
AC   B4HWD7;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN   ORFNames=GM17832;
OS   Drosophila sechellia (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rob3c / Tucson 14021-0248.25;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CH480818; EDW52332.1; -; Genomic_DNA.
DR   RefSeq; XP_002036409.1; XM_002036373.1.
DR   AlphaFoldDB; B4HWD7; -.
DR   SMR; B4HWD7; -.
DR   STRING; 7238.B4HWD7; -.
DR   EnsemblMetazoa; FBtr0200817; FBpp0199309; FBgn0172739.
DR   GeneID; 6611892; -.
DR   KEGG; dse:6611892; -.
DR   HOGENOM; CLU_040504_1_0_1; -.
DR   OMA; QYTRGIG; -.
DR   PhylomeDB; B4HWD7; -.
DR   Proteomes; UP000001292; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR043560; ZGPAT.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR46297; PTHR46297; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..513
FT                   /note="Zinc finger CCCH-type with G patch domain-containing
FT                   protein"
FT                   /id="PRO_0000385207"
FT   DOMAIN          312..358
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   ZN_FING         155..178
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          252..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          411..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          477..513
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        477..497
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        498..513
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   513 AA;  58675 MW;  6D7AA0CEFD99CE67 CRC64;
     MEEYEAQLLV VEQALENAAD DAQRQELLAL KNNLQELLAL TRDTGDEAPT DELPQQGNDL
     DDELQRLKSE LSDLEAAGSS QTALDEERQL ADLRTKYTAM VGEKCSAPHE HSWGTCYHNA
     LICGVDDEVV INSEGVLDAR LRVLFTNPTH REMLPCSYYL EGECRFDEAK CRFSHGALVT
     GSSIRKYNPP DFHKLSRSRP VFALLPDRLW HRGRVLCVNF VEQVCRVRLD GQDHKERERD
     FKFEELYPLT TDQDEDDELS SEESTSSMRD ASSDEAESDM DDLEEARRAR MVELSLFTYK
     PTDRLGAWEE FTRGIGSKLM EKMGYIHGTG LGSEGRGIVT PVSAQILPQG RSLDACMELR
     EAANGDKDYF SVERKLKRAQ RRQRKADEKA YVRESQRVDV FTFLNDRVLG PGESTQQSEQ
     VAKKAKNNEL QQHSTKTLNV ETVRIADEIR RKQRDMAKVK QSLERNSGDA QLQKRLQVQM
     QSHKQELATL QAQERSLSKE QQTRKSKNKM FEF