ID   ZGPAT_DROSI             Reviewed;         513 AA.
AC   B4Q8A7;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN   ORFNames=GD23643;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CM000361; EDX04429.1; -; Genomic_DNA.
DR   RefSeq; XP_002078844.1; XM_002078808.2.
DR   AlphaFoldDB; B4Q8A7; -.
DR   SMR; B4Q8A7; -.
DR   STRING; 7240.B4Q8A7; -.
DR   EnsemblMetazoa; FBtr0223553; FBpp0222045; FBgn0195020.
DR   GeneID; 6731709; -.
DR   HOGENOM; CLU_040504_1_0_1; -.
DR   OMA; QYTRGIG; -.
DR   PhylomeDB; B4Q8A7; -.
DR   Proteomes; UP000000304; Chromosome 2l.
DR   Bgee; FBgn0195020; Expressed in embryo and 3 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR043560; ZGPAT.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR46297; PTHR46297; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..513
FT                   /note="Zinc finger CCCH-type with G patch domain-containing
FT                   protein"
FT                   /id="PRO_0000385208"
FT   DOMAIN          312..358
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   ZN_FING         155..178
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          252..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          477..513
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        477..497
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        498..513
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   513 AA;  58604 MW;  87886B40D737E554 CRC64;
     MEEYEAQLLV VEQALENAAD DAQRQELLAL KNNLQELLAL TRDTGDEAPT DELPQQGNDL
     DDELQRLKSE LSALEAAGSS QTALDEERQL ADLRTKYTAM VGEKCSAPHE HSWGTCYHNA
     LICGVDDEVV INSEGVLDAR LRVLFTNPTH REMLPCSYYL EGECRFDEAK CRFSHGALVT
     GSSIRKYNPP DFHKLSRSRP VFALLPDRLW HRGRVLCVNF VEQVCRVRLD GQDHKERERD
     FKFEELYPLT TDQDEDDELS SEESTSSMRD ASSDEAESDM DDLEEARRAR MVELSLFTYK
     PTDRLGAWEE FTRGIGSKLM EKMGYIHGTG LGSDGRGIVT PVSAQILPQG RSLDACMELR
     EAANGDKDYF SVERKLKRAQ RRQRKADEKA YVRESQRVDV FTFLNDRVLG PGESTQQSEQ
     VAKKAKTNEL QQHSTKTLNV ETVRIADEIR RKQRDMAKVK QSLERNSGDA QLQKRLQVQM
     QSHKQELATL QAQERSLSKE QQTRKSKNKM FEF