ID   ZGPAT_DROVI             Reviewed;         508 AA.
AC   B4M9F7;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN   ORFNames=GJ17921;
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15010-1051.87;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CH940654; EDW57833.1; -; Genomic_DNA.
DR   RefSeq; XP_002057760.1; XM_002057724.2.
DR   AlphaFoldDB; B4M9F7; -.
DR   SMR; B4M9F7; -.
DR   STRING; 7244.FBpp0232338; -.
DR   PRIDE; B4M9F7; -.
DR   EnsemblMetazoa; FBtr0233846; FBpp0232338; FBgn0205089.
DR   GeneID; 6633957; -.
DR   KEGG; dvi:6633957; -.
DR   eggNOG; KOG2185; Eukaryota.
DR   HOGENOM; CLU_040504_1_0_1; -.
DR   InParanoid; B4M9F7; -.
DR   OMA; QYTRGIG; -.
DR   OrthoDB; 1238995at2759; -.
DR   PhylomeDB; B4M9F7; -.
DR   Proteomes; UP000008792; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR043560; ZGPAT.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR46297; PTHR46297; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..508
FT                   /note="Zinc finger CCCH-type with G patch domain-containing
FT                   protein"
FT                   /id="PRO_0000385209"
FT   DOMAIN          309..355
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   ZN_FING         154..177
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          253..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          486..508
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..276
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   508 AA;  57969 MW;  554B66FAC43DB1D6 CRC64;
     MDEYEAQLLV VEQALLVTTD AQQREELIAL RANLEELLAL TRSSETEDIN ETNTQQATDI
     DDELKRFQNE LSSLEGEQTD SQDDQQRLEE LRTKYNALLG EKCSAPHEHS WGALSYHNAL
     ICGVDDELIL DKNGILDVRL RVLFTNPTHR EMLPCNYYLE GECRFDETRC RYSHGALVPG
     AAIKDYNAPD FCRLARNCPV LAKLQDRLWH RGRVLCVNFM EQQCRVRLDG QEHKERERDF
     PFEELFPLIV EEDDELSSDS EETNETDGSD AANESDMDDV EAARQARMVE LSLFTFKPNE
     RLGAWEQYTR GIGSKLMASM GYIHGTGLGS DGRGIVTPVS AQILPQGRSL DACMELREAA
     NGDKDYFSIE RKLKRAQRRQ QAANEKAYER ESKRTDVFAF LNGSVLGQGS QRAENSTKTT
     KIDNLQQHTN KSLNVETVRI ADDIRRKQRD IAKTQQSLAR NAIDSQLQKR LSSQLQSQKQ
     ELATLQAQES SLSKEQQTRK SKNKMFEF