ID   ZGPAT_DROYA             Reviewed;         513 AA.
AC   B4NYQ2;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
GN   ORFNames=GE18884;
OS   Drosophila yakuba (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tai18E2 / Tucson 14021-0261.01;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Transcription repressor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CM000157; EDW88716.1; -; Genomic_DNA.
DR   RefSeq; XP_002089004.1; XM_002088968.2.
DR   AlphaFoldDB; B4NYQ2; -.
DR   SMR; B4NYQ2; -.
DR   STRING; 7245.FBpp0263894; -.
DR   EnsemblMetazoa; FBtr0265402; FBpp0263894; FBgn0236263.
DR   GeneID; 6527937; -.
DR   KEGG; dya:Dyak_GE18884; -.
DR   eggNOG; KOG2185; Eukaryota.
DR   HOGENOM; CLU_040504_1_0_1; -.
DR   OMA; QYTRGIG; -.
DR   OrthoDB; 1238995at2759; -.
DR   PhylomeDB; B4NYQ2; -.
DR   Proteomes; UP000002282; Chromosome 2L.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR043560; ZGPAT.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR46297; PTHR46297; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Repressor; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..513
FT                   /note="Zinc finger CCCH-type with G patch domain-containing
FT                   protein"
FT                   /id="PRO_0000385210"
FT   DOMAIN          312..358
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   ZN_FING         155..178
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          252..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          455..513
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..281
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        464..497
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        498..513
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   513 AA;  58674 MW;  E6E0A725938B6266 CRC64;
     MEEYEAQLLV VEQALENAAD EAQRQDLLAL KNNLQELLAL TRDTGDEAHT DELPQQGDDL
     DDELQRLKSE LSDLEAVGSS QTALDEERQL ADLRTKYTAM VGEKCSAPHE HSWGTCYHNA
     LICGVDDEVV MNSEGVLDAR LRVLFTNPTH REMLPCSYYL EGECRFDETK CRFSHGALVP
     GSSIRKYNPP DFHKLSRSRP VFALLPDRLW HRGRVLCVNF VEQVCRVRLD GQDHKERERD
     FKFEELFPLT TDQDEDDELS SEESNSSMND DSSDEAESDM DDLEEARRAR MVELSLFTFK
     PTERLGAWEE FTRGIGSKLM EKMGYIHGTG LGSDGRGIVT PVSAQILPQG RSLDACMELR
     EAANGDKDYF SVERKLKRAQ RRQRKADEKA YVRESQRVDV FTFLNDSVLG PGESSQQGEQ
     VAKKIKTNEL QQHSTKTLNV ETVRIADEIR RKQRDMAKVK QSLDRNSGDA QLQKRLQVQM
     ESHKQELATL QAQERSLSKE QQTRKSKNKM FEF