ZHD1_ORYSI
ID ZHD1_ORYSI Reviewed; 279 AA.
AC A2Z259;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Zinc-finger homeodomain protein 1;
GN Name=ZHD1; ORFNames=OsI_31693;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Putative transcription factor. {ECO:0000250}.
CC -!- SUBUNIT: Homo- and heterodimer with other ZFHD proteins. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- DOMAIN: The homeodomain differs form the typical one by having namely 4
CC instead of 3 extra amino acids inserted in the loop between helix 1 and
CC helix 2.
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DR EMBL; CM000134; EAZ09420.1; -; Genomic_DNA.
DR AlphaFoldDB; A2Z259; -.
DR SMR; A2Z259; -.
DR STRING; 39946.A2Z259; -.
DR EnsemblPlants; BGIOSGA029617-TA; BGIOSGA029617-PA; BGIOSGA029617.
DR Gramene; BGIOSGA029617-TA; BGIOSGA029617-PA; BGIOSGA029617.
DR HOGENOM; CLU_039237_2_2_1; -.
DR OMA; ETEIMSG; -.
DR Proteomes; UP000007015; Chromosome 9.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006455; Homeodomain_ZF_HD.
DR InterPro; IPR006456; ZF_HD_homeobox_Cys/His_dimer.
DR Pfam; PF04770; ZF-HD_dimer; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01565; homeo_ZF_HD; 1.
DR TIGRFAMs; TIGR01566; ZF_HD_prot_N; 1.
DR PROSITE; PS51523; ZF_HD_DIMER; 1.
PE 3: Inferred from homology;
KW DNA-binding; Homeobox; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..279
FT /note="Zinc-finger homeodomain protein 1"
FT /id="PRO_0000426036"
FT ZN_FING 57..106
FT /note="ZF-HD dimerization-type; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00856"
FT DNA_BIND 215..278
FT /note="Homeobox"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 267
FT /note="Required for DNA-binding"
FT /evidence="ECO:0000250"
SQ SEQUENCE 279 AA; 29496 MW; 8775D33ADC363DC4 CRC64;
MDFDDHDDGD EEMPPMPVSS SYETPPQHGL AGGGMAPKPP GEIGSHVKGP SCGGGRYREC
LKNHAVGIGG HAVDGCGEFM AAGEEGTIDA LRCAACNCHR NFHRKESESL AGEGSPFSPA
AVVPYGATPH HQFSPYYRTP AGYLHHHQHH MAAAAAAAAA AAGGHPQRPL ALPSTSHSGR
DDGDDLSGMV GPMSAVGPLS GMSLGAGPSG SGSGKKRFRT KFTQEQKDKM LAFAERVGWR
IQKHDEAAVQ QFCDEVGVKR HVLKVWMHNN KHTLGKKLP