ID   ZHD2_ORYSI              Reviewed;         290 AA.
AC   A2YWA6;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Zinc-finger homeodomain protein 2;
GN   Name=ZHD2; ORFNames=OsI_29618;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Putative transcription factor. {ECO:0000250}.
CC   -!- SUBUNIT: Homo- and heterodimer with other ZFHD proteins. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- DOMAIN: The homeodomain differs form the typical one by having namely 4
CC       instead of 3 extra amino acids inserted in the loop between helix 1 and
CC       helix 2.
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DR   EMBL; CM000133; EAZ07367.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2YWA6; -.
DR   SMR; A2YWA6; -.
DR   STRING; 39946.A2YWA6; -.
DR   EnsemblPlants; BGIOSGA026798-TA; BGIOSGA026798-PA; BGIOSGA026798.
DR   Gramene; BGIOSGA026798-TA; BGIOSGA026798-PA; BGIOSGA026798.
DR   HOGENOM; CLU_039237_2_2_1; -.
DR   OMA; EMTPMPV; -.
DR   Proteomes; UP000007015; Chromosome 8.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006455; Homeodomain_ZF_HD.
DR   InterPro; IPR006456; ZF_HD_homeobox_Cys/His_dimer.
DR   Pfam; PF04770; ZF-HD_dimer; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   TIGRFAMs; TIGR01565; homeo_ZF_HD; 1.
DR   TIGRFAMs; TIGR01566; ZF_HD_prot_N; 1.
DR   PROSITE; PS51523; ZF_HD_DIMER; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Homeobox; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..290
FT                   /note="Zinc-finger homeodomain protein 2"
FT                   /id="PRO_0000426038"
FT   ZN_FING         63..112
FT                   /note="ZF-HD dimerization-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00856"
FT   DNA_BIND        226..289
FT                   /note="Homeobox"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            278
FT                   /note="Required for DNA-binding"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   290 AA;  29759 MW;  0BD54AA162DDE05A CRC64;
     MDFDDHDEGD GDEEMPPMPL SSGYDAPMQP GLGGGGGGVP KPGGGVGGGG GGGGGGGGGG
     ARYRECLKNH AVGIGGHAVD GCGEFMASGE EGSIDALRCA ACGCHRNFHR KESESPTGVG
     PAEPSAVSPA AISAYGASPH HQFSPYYRTP AGYLHHQQHQ MAAAAAAAAA AAAGGYPQRP
     LALPSTSHSG RDEGDDMSGM VGPMVIGPMV GMSLGSAGPS GSGSGKKRFR TKFTQEQKDK
     MLAFAERLGW RIQKHDEAAV QQFCEEVCVK RHVLKVWMHN NKHTLGKKAP