ID   ZHD2_ORYSJ              Reviewed;         290 AA.
AC   Q6ZB90; A0A0P0XH79; B9G1F7;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Zinc-finger homeodomain protein 2;
DE            Short=OsZHD2;
GN   Name=ZHD2; OrderedLocusNames=Os08g0479400, LOC_Os08g37400;
GN   ORFNames=OJ1113_A10.19, OsJ_27685;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18713354; DOI=10.1111/j.1744-7909.2008.00681.x;
RA   Hu W., dePamphilis C.W., Ma H.;
RT   "Phylogenetic analysis of the plant-specific zinc finger-homeobox and mini
RT   zinc finger gene families.";
RL   J. Integr. Plant Biol. 50:1031-1045(2008).
CC   -!- FUNCTION: Putative transcription factor. {ECO:0000250}.
CC   -!- SUBUNIT: Homo- and heterodimer with other ZFHD proteins. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- DOMAIN: The homeodomain differs form the typical one by having namely 4
CC       instead of 3 extra amino acids inserted in the loop between helix 1 and
CC       helix 2.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EEE68874.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AP004643; BAD09750.1; -; Genomic_DNA.
DR   EMBL; AP008214; BAF23969.1; -; Genomic_DNA.
DR   EMBL; AP014964; BAT05908.1; -; Genomic_DNA.
DR   EMBL; CM000145; EEE68874.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AK109528; BAG98791.1; -; mRNA.
DR   RefSeq; XP_015649557.1; XM_015794071.1.
DR   AlphaFoldDB; Q6ZB90; -.
DR   SMR; Q6ZB90; -.
DR   STRING; 4530.OS08T0479400-01; -.
DR   PaxDb; Q6ZB90; -.
DR   PRIDE; Q6ZB90; -.
DR   EnsemblPlants; Os08t0479400-01; Os08t0479400-01; Os08g0479400.
DR   GeneID; 4345845; -.
DR   Gramene; Os08t0479400-01; Os08t0479400-01; Os08g0479400.
DR   KEGG; osa:4345845; -.
DR   eggNOG; ENOG502QRG0; Eukaryota.
DR   HOGENOM; CLU_039237_2_2_1; -.
DR   InParanoid; Q6ZB90; -.
DR   OMA; EMTPMPV; -.
DR   OrthoDB; 1229084at2759; -.
DR   Proteomes; UP000000763; Chromosome 8.
DR   Proteomes; UP000007752; Chromosome 8.
DR   Proteomes; UP000059680; Chromosome 8.
DR   Genevisible; Q6ZB90; OS.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006455; Homeodomain_ZF_HD.
DR   InterPro; IPR006456; ZF_HD_homeobox_Cys/His_dimer.
DR   Pfam; PF04770; ZF-HD_dimer; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   TIGRFAMs; TIGR01565; homeo_ZF_HD; 1.
DR   TIGRFAMs; TIGR01566; ZF_HD_prot_N; 1.
DR   PROSITE; PS51523; ZF_HD_DIMER; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..290
FT                   /note="Zinc-finger homeodomain protein 2"
FT                   /id="PRO_0000426037"
FT   ZN_FING         63..112
FT                   /note="ZF-HD dimerization-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00856"
FT   DNA_BIND        226..289
FT                   /note="Homeobox"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            278
FT                   /note="Required for DNA-binding"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   290 AA;  29759 MW;  0BD54AA162DDE05A CRC64;
     MDFDDHDEGD GDEEMPPMPL SSGYDAPMQP GLGGGGGGVP KPGGGVGGGG GGGGGGGGGG
     ARYRECLKNH AVGIGGHAVD GCGEFMASGE EGSIDALRCA ACGCHRNFHR KESESPTGVG
     PAEPSAVSPA AISAYGASPH HQFSPYYRTP AGYLHHQQHQ MAAAAAAAAA AAAGGYPQRP
     LALPSTSHSG RDEGDDMSGM VGPMVIGPMV GMSLGSAGPS GSGSGKKRFR TKFTQEQKDK
     MLAFAERLGW RIQKHDEAAV QQFCEEVCVK RHVLKVWMHN NKHTLGKKAP