ID   ZHD3_ORYSJ              Reviewed;         329 AA.
AC   Q2QW44; Q0IPF6;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 3.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Zinc-finger homeodomain protein 3;
DE            Short=OsZHD3;
GN   Name=ZHD3; OrderedLocusNames=Os12g0208900, LOC_Os12g10630;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT   genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18713354; DOI=10.1111/j.1744-7909.2008.00681.x;
RA   Hu W., dePamphilis C.W., Ma H.;
RT   "Phylogenetic analysis of the plant-specific zinc finger-homeobox and mini
RT   zinc finger gene families.";
RL   J. Integr. Plant Biol. 50:1031-1045(2008).
CC   -!- FUNCTION: Putative transcription factor. {ECO:0000250}.
CC   -!- SUBUNIT: Homo- and heterodimer with other ZFHD proteins. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- DOMAIN: The homeodomain differs form the typical one by having namely 4
CC       instead of 3 extra amino acids inserted in the loop between helix 1 and
CC       helix 2.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABA96146.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAF29409.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DP000011; ABA96146.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008218; BAF29409.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014968; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015618832.1; XM_015763346.1.
DR   AlphaFoldDB; Q2QW44; -.
DR   SMR; Q2QW44; -.
DR   STRING; 39947.Q2QW44; -.
DR   PaxDb; Q2QW44; -.
DR   PRIDE; Q2QW44; -.
DR   GeneID; 4351766; -.
DR   KEGG; osa:4351766; -.
DR   eggNOG; ENOG502QSB4; Eukaryota.
DR   OrthoDB; 1302249at2759; -.
DR   Proteomes; UP000000763; Chromosome 12.
DR   Proteomes; UP000059680; Chromosome 12.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006455; Homeodomain_ZF_HD.
DR   InterPro; IPR006456; ZF_HD_homeobox_Cys/His_dimer.
DR   Pfam; PF04770; ZF-HD_dimer; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   TIGRFAMs; TIGR01565; homeo_ZF_HD; 1.
DR   TIGRFAMs; TIGR01566; ZF_HD_prot_N; 1.
DR   PROSITE; PS51523; ZF_HD_DIMER; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Homeobox; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..329
FT                   /note="Zinc-finger homeodomain protein 3"
FT                   /id="PRO_0000426039"
FT   ZN_FING         74..123
FT                   /note="ZF-HD dimerization-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00856"
FT   DNA_BIND        193..256
FT                   /note="Homeobox"
FT   REGION          24..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          252..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        261..284
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            245
FT                   /note="Required for DNA-binding"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   329 AA;  34952 MW;  B4822362A5CB63D6 CRC64;
     MDLSGAQGEL PLPMHAAASP YLGLHHDHHH HHGGGGGGGG MNGRHMSPPT PPAAAEESKA
     VVVVSSSATA AARYRECLKN HAAAIGGSAT DGCGEFMPGG EEGSLDALRC SACGCHRNFH
     RKELDAAAAP PLHHHHHQLL GVGAHPRGHG HHHHHLLVAA LPPPTRMVMP LSAMHTSESD
     DAAARPGGGA AARKRFRTKF TAEQKARMLG FAEEVGWRLQ KLEDAVVQRF CQEVGVKRRV
     LKVWMHNNKH TLARRHLHPS PAAAAGDDDD DGAPPPHPDP RRRELAAAAA PPPAPVTQHI
     KKSVDNKSLI SSLAALHCIA LLLFHQIDA