ZHD4_ORYSJ
ID ZHD4_ORYSJ Reviewed; 417 AA.
AC Q53N87; A0A0P0Y0R8; Q0ITH9;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 2.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Zinc-finger homeodomain protein 4;
DE Short=OsZHD4;
GN Name=ZHD4; OrderedLocusNames=Os11g0243300, LOC_Os11g13930;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18713354; DOI=10.1111/j.1744-7909.2008.00681.x;
RA Hu W., dePamphilis C.W., Ma H.;
RT "Phylogenetic analysis of the plant-specific zinc finger-homeobox and mini
RT zinc finger gene families.";
RL J. Integr. Plant Biol. 50:1031-1045(2008).
CC -!- FUNCTION: Putative transcription factor. {ECO:0000250}.
CC -!- SUBUNIT: Homo- and heterodimer with other ZFHD proteins. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- DOMAIN: The homeodomain differs form the typical one by having namely 4
CC instead of 3 extra amino acids inserted in the loop between helix 1 and
CC helix 2.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAX95984.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=ABA92344.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF27957.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC135460; AAX95984.1; ALT_SEQ; Genomic_DNA.
DR EMBL; DP000010; ABA92344.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008217; BAF27957.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014967; BAT13395.1; -; Genomic_DNA.
DR EMBL; AK287714; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q53N87; -.
DR SMR; Q53N87; -.
DR STRING; 4530.OS11T0243300-01; -.
DR PaxDb; Q53N87; -.
DR PRIDE; Q53N87; -.
DR EnsemblPlants; Os11t0243300-01; Os11t0243300-01; Os11g0243300.
DR Gramene; Os11t0243300-01; Os11t0243300-01; Os11g0243300.
DR eggNOG; ENOG502QSB4; Eukaryota.
DR HOGENOM; CLU_039237_2_1_1; -.
DR InParanoid; Q53N87; -.
DR OMA; ELHRHEH; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR Genevisible; Q53N87; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006455; Homeodomain_ZF_HD.
DR InterPro; IPR006456; ZF_HD_homeobox_Cys/His_dimer.
DR Pfam; PF04770; ZF-HD_dimer; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01565; homeo_ZF_HD; 1.
DR TIGRFAMs; TIGR01566; ZF_HD_prot_N; 1.
DR PROSITE; PS51523; ZF_HD_DIMER; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Homeobox; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..417
FT /note="Zinc-finger homeodomain protein 4"
FT /id="PRO_0000426040"
FT ZN_FING 145..194
FT /note="ZF-HD dimerization-type; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00856"
FT DNA_BIND 303..366
FT /note="Homeobox"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 31..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 361..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..417
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 355
FT /note="Required for DNA-binding"
FT /evidence="ECO:0000250"
SQ SEQUENCE 417 AA; 43962 MW; 9269DC408F135C02 CRC64;
MVSILQLQTR TEASPASSAS AAATRIFAVR RQQQEQEGEE EEEEFEFQER MDLSGAQGEL
PIPMHASAAA SPFAGMGAHG GAGGGHVVEL HRHEHVGNNG QAMAMASPPP TNVAVAAEQE
GSPVAGKKRG GMAVVGGGGG VAVKYRECLK NHAAAIGGNA TDGCGEFMPS GEEGSLEALK
CSACGCHRNF HRKEADDLDA DSCAAALRAA AGRHHHLLGP ALPHHHHKNG GGLLVAGGDP
YGAAYAAARA LPPPPPPPPH GHHHHHQIIM PLNMIHTSES DEMDVSGGGG GVGRGGGSSS
SSKKRFRTKF TAEQKARMLE FAERVGWRLQ KLDDAMVHHF CQEIGVKRRV LKVWMHNNKH
NLAKKPLPSS PPPPPQIPPM SMPPSPPPPQ IPPMSMPPSP PPMPMPMPPS PPQLKLE
