CC184_MOUSE
ID CC184_MOUSE Reviewed; 191 AA.
AC Q8BMK5; Q4VBF4; Q8BV27;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Coiled-coil domain-containing protein 184;
GN Name=Ccdc184;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Medulla oblongata;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=C57BL/6J; TISSUE=Brain, and Eye;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8BMK5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8BMK5-2; Sequence=VSP_033768;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH90621.2; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAH95968.3; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AK030707; BAC27091.1; -; mRNA.
DR EMBL; AK080988; BAC38107.1; -; mRNA.
DR EMBL; BC090621; AAH90621.2; ALT_INIT; mRNA.
DR EMBL; BC095968; AAH95968.3; ALT_INIT; mRNA.
DR CCDS; CCDS49718.1; -. [Q8BMK5-1]
DR RefSeq; NP_808384.2; NM_177716.3. [Q8BMK5-1]
DR AlphaFoldDB; Q8BMK5; -.
DR STRING; 10090.ENSMUSP00000031914; -.
DR PhosphoSitePlus; Q8BMK5; -.
DR MaxQB; Q8BMK5; -.
DR PaxDb; Q8BMK5; -.
DR PeptideAtlas; Q8BMK5; -.
DR PRIDE; Q8BMK5; -.
DR ProteomicsDB; 265298; -. [Q8BMK5-1]
DR ProteomicsDB; 265299; -. [Q8BMK5-2]
DR Antibodypedia; 25636; 74 antibodies from 15 providers.
DR Ensembl; ENSMUST00000031914; ENSMUSP00000031914; ENSMUSG00000029875. [Q8BMK5-1]
DR GeneID; 239650; -.
DR KEGG; mmu:239650; -.
DR UCSC; uc011zys.1; mouse. [Q8BMK5-1]
DR CTD; 387856; -.
DR MGI; MGI:2146066; Ccdc184.
DR VEuPathDB; HostDB:ENSMUSG00000029875; -.
DR eggNOG; ENOG502RNYW; Eukaryota.
DR GeneTree; ENSGT00390000002978; -.
DR HOGENOM; CLU_125035_0_0_1; -.
DR InParanoid; Q8BMK5; -.
DR OMA; HCERSES; -.
DR OrthoDB; 1296471at2759; -.
DR PhylomeDB; Q8BMK5; -.
DR TreeFam; TF337201; -.
DR BioGRID-ORCS; 239650; 2 hits in 71 CRISPR screens.
DR ChiTaRS; Ccdc184; mouse.
DR PRO; PR:Q8BMK5; -.
DR Proteomes; UP000000589; Chromosome 15.
DR RNAct; Q8BMK5; protein.
DR Bgee; ENSMUSG00000029875; Expressed in facial nucleus and 141 other tissues.
DR Genevisible; Q8BMK5; MM.
DR GO; GO:0005737; C:cytoplasm; ISO:MGI.
DR InterPro; IPR031458; DUF4677.
DR PANTHER; PTHR31554; PTHR31554; 1.
DR Pfam; PF15726; DUF4677; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..191
FT /note="Coiled-coil domain-containing protein 184"
FT /id="PRO_0000335682"
FT REGION 101..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 39..68
FT /evidence="ECO:0000255"
FT VAR_SEQ 1..39
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_033768"
FT CONFLICT 87
FT /note="V -> F (in Ref. 1; BAC38107)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 191 AA; 20184 MW; 70185AE2087066A0 CRC64;
MEDSLLEIMT KDGGDMPAPL EVSTVPAVGD VISGEYNGGM KELMEHLKAQ LQALFEDVRA
MRGALDEQAS HIQVLSDDVC ANQRAIVSMC QIMTTAPRQG GLGVAGGKGS FPSVPHEPET
PSPGIEDSGL LGRDPDEDED EEEKETPNPA TPTSHCELSE SPGLLGEDGP LVEPPDLPDI
TLLQLEGEAS L
