ID   ZHD5_ORYSI              Reviewed;         232 AA.
AC   A2WSZ6;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Zinc-finger homeodomain protein 5;
GN   Name=ZHD5; ORFNames=OsI_02986;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Putative transcription factor. {ECO:0000250}.
CC   -!- SUBUNIT: Homo- and heterodimer with other ZFHD proteins. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- DOMAIN: The homeodomain differs form the typical one by having namely 4
CC       instead of 3 extra amino acids inserted in the loop between helix 1 and
CC       helix 2.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM000126; EAY75092.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2WSZ6; -.
DR   SMR; A2WSZ6; -.
DR   STRING; 39946.A2WSZ6; -.
DR   EnsemblPlants; BGIOSGA001155-TA; BGIOSGA001155-PA; BGIOSGA001155.
DR   Gramene; BGIOSGA001155-TA; BGIOSGA001155-PA; BGIOSGA001155.
DR   HOGENOM; CLU_039237_2_2_1; -.
DR   OMA; KMYSFSE; -.
DR   Proteomes; UP000007015; Chromosome 1.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006455; Homeodomain_ZF_HD.
DR   InterPro; IPR006456; ZF_HD_homeobox_Cys/His_dimer.
DR   Pfam; PF04770; ZF-HD_dimer; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   TIGRFAMs; TIGR01565; homeo_ZF_HD; 1.
DR   TIGRFAMs; TIGR01566; ZF_HD_prot_N; 1.
DR   PROSITE; PS51523; ZF_HD_DIMER; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Homeobox; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..232
FT                   /note="Zinc-finger homeodomain protein 5"
FT                   /id="PRO_0000426042"
FT   ZN_FING         40..86
FT                   /note="ZF-HD dimerization-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00856"
FT   DNA_BIND        159..222
FT                   /note="Homeobox"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        135..152
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            211
FT                   /note="Required for DNA-binding"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   232 AA;  25399 MW;  1ABCA8F29574C757 CRC64;
     MELSEHEEDA GDVGGGCSSP PTPPHRVLTS AAPETIRCRY HECLRNHAAA SGGHVVDGCG
     EFMPASTEEP LACAACGCHR SFHRRDPSPG RAGAARLLQL HLPASINSRA PPALLLPPAA
     AASKQGLPFP GYGTPSGGTG TTTASSSDER LRPSPVQPRR RSRTTFTREQ KEQMLAFAER
     VGWRIQRQEE ATVEHFCAQV GVRRQALKVW MHNNKHSFKQ KQQQENRQEQ QQ