ZHD7_ORYSJ
ID ZHD7_ORYSJ Reviewed; 427 AA.
AC Q8S3Q9; A0A0P0VNS5;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Zinc-finger homeodomain protein 7;
DE Short=OsZHD7;
GN Name=ZHD7; OrderedLocusNames=Os02g0706600, LOC_Os02g47770;
GN ORFNames=49D11.22, OSJNBb0060O16.6, P0680A05.32;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15232225;
RA Park Y.-J., Dixit A., Yoo J.-W., Bennetzen J.;
RT "Further evidence of microcolinearity between barley and rice genomes at
RT two orthologous regions.";
RL Mol. Cells 17:492-502(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18713354; DOI=10.1111/j.1744-7909.2008.00681.x;
RA Hu W., dePamphilis C.W., Ma H.;
RT "Phylogenetic analysis of the plant-specific zinc finger-homeobox and mini
RT zinc finger gene families.";
RL J. Integr. Plant Biol. 50:1031-1045(2008).
CC -!- FUNCTION: Putative transcription factor. {ECO:0000250}.
CC -!- SUBUNIT: Homo- and heterodimer with other ZFHD proteins. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- DOMAIN: The homeodomain differs form the typical one by having namely 4
CC instead of 3 extra amino acids inserted in the loop between helix 1 and
CC helix 2.
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DR EMBL; AF480496; AAL87169.1; -; Genomic_DNA.
DR EMBL; AP005323; BAD08049.1; -; Genomic_DNA.
DR EMBL; AP005844; BAD08093.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS80524.1; -; Genomic_DNA.
DR RefSeq; XP_015626824.1; XM_015771338.1.
DR AlphaFoldDB; Q8S3Q9; -.
DR SMR; Q8S3Q9; -.
DR PaxDb; Q8S3Q9; -.
DR PRIDE; Q8S3Q9; -.
DR EnsemblPlants; Os02t0706600-00; Os02t0706600-00; Os02g0706600.
DR GeneID; 4330466; -.
DR Gramene; Os02t0706600-00; Os02t0706600-00; Os02g0706600.
DR KEGG; osa:4330466; -.
DR eggNOG; ENOG502QS6S; Eukaryota.
DR HOGENOM; CLU_643092_0_0_1; -.
DR InParanoid; Q8S3Q9; -.
DR OMA; HRVGWRI; -.
DR OrthoDB; 1397036at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q8S3Q9; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR006455; Homeodomain_ZF_HD.
DR InterPro; IPR006456; ZF_HD_homeobox_Cys/His_dimer.
DR Pfam; PF04770; ZF-HD_dimer; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01565; homeo_ZF_HD; 1.
DR TIGRFAMs; TIGR01566; ZF_HD_prot_N; 1.
DR PROSITE; PS51523; ZF_HD_DIMER; 1.
PE 3: Inferred from homology;
KW DNA-binding; Homeobox; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..427
FT /note="Zinc-finger homeodomain protein 7"
FT /id="PRO_0000426045"
FT ZN_FING 163..211
FT /note="ZF-HD dimerization-type; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00856"
FT DNA_BIND 318..381
FT /note="Homeobox"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 91..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..28
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..397
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 400..418
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 370
FT /note="Required for DNA-binding"
FT /evidence="ECO:0000250"
SQ SEQUENCE 427 AA; 45059 MW; 6830A97BBE113DCB CRC64;
MEYKRSSHVE EEEEEEEEED DEEEDEEEQG HHQYTTAAAQ QQLHPQVLGS SASSPSSLMD
SAAFSRPLLP PNLSLVSPSA AAAAAPGGSY LHAAHHHGQG RRVEAPGGES QHHLQRHHEP
ARNGVLGGVA GAHAASTLAL VGGGGGGPRG GEGAAGEAPT WRYRECLKNH AARMGAHVLD
GCGEFMSSPG DGAAALACAA CGCHRSFHRR EPAVVAPASL SLCPASASAS AAAGLVSLSP
SATPTGANSS RLMPLLLAPP HMQKRPPVLP VSPASAPAAL AESSSEELRP PPLPSSHPHA
HAAAVVAASA SAPPGPSKKR FRTKFTAEQK ERMREFAHRV GWRIHKPDAA AVDAFCAQVG
VSRRVLKVWM HNNKHLAKTP PSPTSQPPPP PLHHDPSPPP PPHHHHHHHH HHHPPQHHQQ
QQQQHDA