ID   CC186_PONAB             Reviewed;         689 AA.
AC   Q5R9B3; Q5R7J3;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 2.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Coiled-coil domain-containing protein 186;
DE   Flags: Fragment;
GN   Name=CCDC186;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAH91647.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=CAH92267.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CR859476; CAH91647.1; ALT_INIT; mRNA.
DR   EMBL; CR860122; CAH92267.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001125967.1; NM_001132495.1.
DR   AlphaFoldDB; Q5R9B3; -.
DR   SMR; Q5R9B3; -.
DR   STRING; 9601.ENSPPYP00000003112; -.
DR   GeneID; 100172903; -.
DR   KEGG; pon:100172903; -.
DR   CTD; 55088; -.
DR   eggNOG; KOG0992; Eukaryota.
DR   eggNOG; KOG1836; Eukaryota.
DR   Proteomes; UP000001595; Unplaced.
DR   InterPro; IPR038830; CCDC186.
DR   PANTHER; PTHR18911; PTHR18911; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Phosphoprotein; Reference proteome.
FT   CHAIN           <1..689
FT                   /note="Coiled-coil domain-containing protein 186"
FT                   /id="PRO_0000089825"
FT   REGION          493..541
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          20..503
FT                   /evidence="ECO:0000255"
FT   COILED          550..594
FT                   /evidence="ECO:0000255"
FT   COILED          646..685
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        503..541
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         531
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8C9S4"
FT   CONFLICT        536
FT                   /note="G -> E (in Ref. 1; CAH91647)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        549
FT                   /note="K -> N (in Ref. 1; CAH91647)"
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
SQ   SEQUENCE   689 AA;  80366 MW;  C55BC2C6D63C1396 CRC64;
     VGLIKENKKH QELFVDICSE KDNLREELKK RTETEKQHMN TIKQLESRIE ELNKEVNASR
     DKLVAQDVTA KNAIQQLHKE MAQRMEQANK KCEEARQEKE AMVMKYVRGE KESLDLRKEK
     ETLEKKLRDA NKELEKNTNK IKQLSQEKGR LHQLYETKEG ETTRLIREID KLKEDINSHV
     IEVKWAQNKL KAEMDSHKET KDKLKETTTK LTQAKEEADQ IRKNCQDMIK TYQESEEIKS
     NELDAKLRVT KGELEKQMQE KSDQLEMHHA KIKELEDLKR TFKEGMDELR TLRTKVKCLE
     DERLRTEDEL SKYKEIINRQ KAEIQNLLDK VKIVDQLQEQ LQRGKQEIEN LKEEVESLNS
     LISDLQKDIE GSRKRESELL LFTERLTSKN AQLQSESNSL QSQFDKLSCS ESQLQSQCEQ
     MKQTNINLES RLLKEEELRK EEVQTLQAEL TCRQTEVKAL STQVEELKDE LVTQRRKHAS
     SIKDLTKQLQ QARRKLDQVE NGSYDKEVSS MGSRSSSSGS LNARSSAEDR SPENTGSSVA
     VDNFPQVDKA MLIERIVRLQ KAHARKNEKI EFMEDHIKQL VEEIRKKTKI IQSYILREES
     GTLSSEASDF NKVHLSRRGG IMASLYTSHP ADNGLTLELS LEINRKLQAV LEDTLLKNIT
     LKENLQTLGT EIERLIKHQH ELEQRTKKT