ZIP10_ARATH
ID ZIP10_ARATH Reviewed; 364 AA.
AC Q8W245; Q9SHF4;
DT 26-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT 26-SEP-2003, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Probable zinc transporter 10;
DE AltName: Full=ZRT/IRT-like protein 10;
DE Flags: Precursor;
GN Name=ZIP10; OrderedLocusNames=At1g31260; ORFNames=T19E23.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11500563; DOI=10.1104/pp.126.4.1646;
RA Maeser P., Thomine S., Schroeder J.I., Ward J.M., Hirschi K., Sze H.,
RA Talke I.N., Amtmann A., Maathuis F.J.M., Sanders D., Harper J.F.,
RA Tchieu J., Gribskov M., Persans M.W., Salt D.E., Kim S.A., Guerinot M.L.;
RT "Phylogenetic relationships within cation transporter families of
RT Arabidopsis.";
RL Plant Physiol. 126:1646-1667(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Probably mediates zinc uptake from the rhizosphere.
CC {ECO:0000250}.
CC -!- INTERACTION:
CC Q8W245; P94077: LSD1; NbExp=3; IntAct=EBI-6956003, EBI-5849461;
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL38436.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF369913; AAL38436.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC007654; AAF24597.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31333.1; -; Genomic_DNA.
DR RefSeq; NP_174411.2; NM_102864.2.
DR AlphaFoldDB; Q8W245; -.
DR BioGRID; 25249; 2.
DR IntAct; Q8W245; 1.
DR MINT; Q8W245; -.
DR STRING; 3702.AT1G31260.1; -.
DR PaxDb; Q8W245; -.
DR PRIDE; Q8W245; -.
DR EnsemblPlants; AT1G31260.1; AT1G31260.1; AT1G31260.
DR GeneID; 840014; -.
DR Gramene; AT1G31260.1; AT1G31260.1; AT1G31260.
DR KEGG; ath:AT1G31260; -.
DR Araport; AT1G31260; -.
DR TAIR; locus:2197520; AT1G31260.
DR eggNOG; KOG1558; Eukaryota.
DR HOGENOM; CLU_027089_3_0_1; -.
DR InParanoid; Q8W245; -.
DR OMA; KAEMANI; -.
DR OrthoDB; 981397at2759; -.
DR PhylomeDB; Q8W245; -.
DR PRO; PR:Q8W245; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8W245; differential.
DR Genevisible; Q8W245; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0071577; P:zinc ion transmembrane transport; IBA:GO_Central.
DR InterPro; IPR003689; ZIP.
DR InterPro; IPR004698; Zn/Fe_permease_fun/pln.
DR Pfam; PF02535; Zip; 1.
DR TIGRFAMs; TIGR00820; zip; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Ion transport; Membrane; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..364
FT /note="Probable zinc transporter 10"
FT /id="PRO_0000041647"
FT TOPO_DOM 29..52
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 74..85
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 107..125
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 126..146
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 147..209
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 231..241
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 263..271
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 293..303
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 325..343
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 344..364
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 364 AA; 39489 MW; 4747CFE90E6B92F2 CRC64;
MTKSHVIFSA SIALFLLLSI SHFPGALSQS NKDCQSKSNY SCIDKNKALD LKLLSIFSIL
ITSLIGVCLP FFARSIPAFQ PEKSHFLIVK SFASGIILST GFMHVLPDSF EMLSSPCLND
NPWHKFPFAG FVAMMSAVFT LMVDSITTSV FTKSGRKDLR ADVASVETPD QEIGHVQVHG
HVHSHTLPHN LHGENDKELG SYLQLLRYRI LAIVLELGIV VQSIVIGLSV GDTNNTCTIK
GLVAALCFHQ MFEGMGLGGC ILQAEYGWVK KAVMAFFFAV TTPFGVVLGM ALSKTYKENS
PESLITVGLL NASSAGLLIY MALVDLLAAD FMGQKMQRSI KLQLKSYAAV LLGAGGMSVM
AKWA
