ZIP1_ORYSJ
ID ZIP1_ORYSJ Reviewed; 352 AA.
AC Q94DG6; A0A0P0VDH4; Q7XZS7;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Zinc transporter 1;
DE AltName: Full=ZRT/IRT-like protein 1;
DE Short=OsZIP1;
DE Flags: Precursor;
GN Name=ZIP1; OrderedLocusNames=Os01g0972200, LOC_Os01g74110;
GN ORFNames=P0518C01.26;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, AND
RP TISSUE SPECIFICITY.
RC STRAIN=cv. Nipponbare;
RX PubMed=12970480; DOI=10.1104/pp.103.026815;
RA Ramesh S.A., Shin R., Eide D.J., Schachtman D.P.;
RT "Differential metal selectivity and gene expression of two zinc
RT transporters from rice.";
RL Plant Physiol. 133:126-134(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- FUNCTION: Zinc transporter that may mediate zinc uptake from the
CC rhizosphere. May also transport other divalent cations.
CC {ECO:0000269|PubMed:12970480}.
CC -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC Kinetic parameters:
CC KM=16.3 uM for Zn(2+) {ECO:0000269|PubMed:12970480};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in vascular bundles of roots and leaves.
CC {ECO:0000269|PubMed:12970480}.
CC -!- INDUCTION: By zinc deficiency in roots and shoots.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000305}.
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DR EMBL; AY302058; AAP59425.1; -; mRNA.
DR EMBL; AP003277; BAB63683.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF07454.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS76436.1; -; Genomic_DNA.
DR RefSeq; XP_015633357.1; XM_015777871.1.
DR AlphaFoldDB; Q94DG6; -.
DR SMR; Q94DG6; -.
DR STRING; 4530.OS01T0972200-00; -.
DR TCDB; 2.A.5.3.4; the zinc (zn(2+))-iron (fe(2+)) permease (zip) family.
DR PaxDb; Q94DG6; -.
DR PRIDE; Q94DG6; -.
DR EnsemblPlants; Os01t0972200-00; Os01t0972200-00; Os01g0972200.
DR GeneID; 4326394; -.
DR Gramene; Os01t0972200-00; Os01t0972200-00; Os01g0972200.
DR KEGG; osa:4326394; -.
DR eggNOG; KOG1558; Eukaryota.
DR HOGENOM; CLU_046211_0_0_1; -.
DR InParanoid; Q94DG6; -.
DR OMA; FGLLAKW; -.
DR OrthoDB; 981397at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; Q94DG6; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0071577; P:zinc ion transmembrane transport; IBA:GO_Central.
DR GO; GO:0006829; P:zinc ion transport; IDA:UniProtKB.
DR InterPro; IPR003689; ZIP.
DR Pfam; PF02535; Zip; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Ion transport; Membrane; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport.
FT SIGNAL 1..29
FT /evidence="ECO:0000255"
FT CHAIN 30..352
FT /note="Zinc transporter 1"
FT /id="PRO_0000398325"
FT TOPO_DOM 30..56
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 78..87
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 109..127
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 149..200
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 222..230
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 252..262
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 284..296
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 318..330
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 331..351
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 352
FT /note="Extracellular"
FT /evidence="ECO:0000255"
SQ SEQUENCE 352 AA; 37447 MW; 35453461D2978FB0 CRC64;
MARTMTMRVS SLLVAVVLLA ALSFQACSGH GGINDGDGQV DAPATPASSS GVRSKGLIAV
KVWCLVILLV FTFAGGVSPY FYRWNESFLL LGTQFAAGVF LGTALMHFLA DSTSTFKGLT
TNQYPFSFML TCVGFLLTML SDLVIAAVAR RSAAAGVSDN QVSEQQQRQQ AEGAVMSRKE
EEAAAVAHPA MLVRTSSFED AVLLIVALCF HSVFEGIAIG VSASKSEAWR NLWTIGLHKI
FAAVAMGIAL LRMIPKRPFL MTVVYSLAFA VSSPVGVGIG IAIDATSQGR AADWTYAISM
GLATGVFIYV AINHLIAKGY RPHHPTAADK PLFKFLAVLL GVAVMAVVMI WD
