ZIP6_ARATH
ID ZIP6_ARATH Reviewed; 341 AA.
AC O64738;
DT 26-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Zinc transporter 6, chloroplastic;
DE AltName: Full=ZRT/IRT-like protein 6;
DE Flags: Precursor;
GN Name=ZIP6; OrderedLocusNames=At2g30080; ORFNames=T27E13.18;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11500563; DOI=10.1104/pp.126.4.1646;
RA Maeser P., Thomine S., Schroeder J.I., Ward J.M., Hirschi K., Sze H.,
RA Talke I.N., Amtmann A., Maathuis F.J.M., Sanders D., Harper J.F.,
RA Tchieu J., Gribskov M., Persans M.W., Salt D.E., Kim S.A., Guerinot M.L.;
RT "Phylogenetic relationships within cation transporter families of
RT Arabidopsis.";
RL Plant Physiol. 126:1646-1667(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: May play a role in the transport of zinc in the plastids.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000305}.
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DR EMBL; AF369910; AAL38433.1; -; Genomic_DNA.
DR EMBL; AC004165; AAC16964.1; -; Genomic_DNA.
DR EMBL; AC004680; AAM14983.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08342.1; -; Genomic_DNA.
DR PIR; T02478; T02478.
DR RefSeq; NP_180569.1; NM_128563.2.
DR AlphaFoldDB; O64738; -.
DR SMR; O64738; -.
DR STRING; 3702.AT2G30080.1; -.
DR PaxDb; O64738; -.
DR PRIDE; O64738; -.
DR ProteomicsDB; 232334; -.
DR EnsemblPlants; AT2G30080.1; AT2G30080.1; AT2G30080.
DR GeneID; 817559; -.
DR Gramene; AT2G30080.1; AT2G30080.1; AT2G30080.
DR KEGG; ath:AT2G30080; -.
DR Araport; AT2G30080; -.
DR TAIR; locus:2045634; AT2G30080.
DR eggNOG; KOG1558; Eukaryota.
DR HOGENOM; CLU_027089_3_0_1; -.
DR InParanoid; O64738; -.
DR OMA; ASQTWLK; -.
DR OrthoDB; 981397at2759; -.
DR PhylomeDB; O64738; -.
DR PRO; PR:O64738; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O64738; baseline and differential.
DR Genevisible; O64738; AT.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0009624; P:response to nematode; HEP:TAIR.
DR GO; GO:0071577; P:zinc ion transmembrane transport; IBA:GO_Central.
DR InterPro; IPR003689; ZIP.
DR InterPro; IPR004698; Zn/Fe_permease_fun/pln.
DR Pfam; PF02535; Zip; 1.
DR TIGRFAMs; TIGR00820; zip; 1.
PE 3: Inferred from homology;
KW Chloroplast; Ion transport; Membrane; Plastid; Reference proteome;
KW Thylakoid; Transit peptide; Transmembrane; Transmembrane helix; Transport;
KW Zinc; Zinc transport.
FT TRANSIT 1..?
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN ?..341
FT /note="Zinc transporter 6, chloroplastic"
FT /id="PRO_0000041644"
FT TOPO_DOM ?..27
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 49..61
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 83..102
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..179
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 201..211
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 233..243
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 265..280
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 281..301
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 302..320
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 321..341
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 341 AA; 36021 MW; 281C9388F0AF2EE0 CRC64;
MASCVTGTEA AIRAAACRDG EEASHLKIVA VFAIFLTSVF GVWGPVLLAK YFHGKPLYDK
AILVIKCFAA GVILSTSLVH VLPEAFESLA DCQVSSRHPW KDFPFAGLVT MIGAITALLV
DLTASEHMGH GGGGGGDGGM EYMPVGKAVG GLEMKEGKCG ADLEIQENSE EEIVKMKQRL
VSQVLEIGII FHSVIIGVTM GMSQNKCTIR PLIAALSFHQ IFEGLGLGGC IAQAGFKAGT
VVYMCLMFAV TTPLGIVLGM VIFAATGYDD QNPNALIMEG LLGSFSSGIL IYMALVDLIA
LDFFHNKMLT TCGESGSRLK KLCFVALVLG SASMSLLALW A
