ZIP6_ORYSJ
ID ZIP6_ORYSJ Reviewed; 395 AA.
AC Q6L8F9; A0A0P0WIB2;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Zinc transporter 6;
DE AltName: Full=ZRT/IRT-like protein 6;
DE Short=OsZIP6;
DE Flags: Precursor;
GN Name=ZIP6; OrderedLocusNames=Os05g0164800, LOC_Os05g07210;
GN ORFNames=OSJNBa0027N19.9;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16263903; DOI=10.1093/jxb/eri317;
RA Ishimaru Y., Suzuki M., Kobayashi T., Takahashi M., Nakanishi H., Mori S.,
RA Nishizawa N.K.;
RT "OsZIP4, a novel zinc-regulated zinc transporter in rice.";
RL J. Exp. Bot. 56:3207-3214(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Zinc transporter that may be involved in zinc uptake from the
CC rhizosphere. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000305}.
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DR EMBL; AB126088; BAD18966.1; -; mRNA.
DR EMBL; AC134341; AAT69626.1; -; Genomic_DNA.
DR EMBL; AP008211; BAF16656.1; -; Genomic_DNA.
DR EMBL; AP014961; BAS92435.1; -; Genomic_DNA.
DR EMBL; AK103730; BAG96232.1; -; mRNA.
DR EMBL; AK120502; BAH00042.1; -; mRNA.
DR RefSeq; XP_015640855.1; XM_015785369.1.
DR AlphaFoldDB; Q6L8F9; -.
DR STRING; 4530.OS05T0164800-02; -.
DR PaxDb; Q6L8F9; -.
DR PRIDE; Q6L8F9; -.
DR EnsemblPlants; Os05t0164800-01; Os05t0164800-01; Os05g0164800.
DR EnsemblPlants; Os05t0164800-02; Os05t0164800-02; Os05g0164800.
DR GeneID; 4337908; -.
DR Gramene; Os05t0164800-01; Os05t0164800-01; Os05g0164800.
DR Gramene; Os05t0164800-02; Os05t0164800-02; Os05g0164800.
DR KEGG; osa:4337908; -.
DR eggNOG; KOG1558; Eukaryota.
DR HOGENOM; CLU_027089_3_0_1; -.
DR InParanoid; Q6L8F9; -.
DR OMA; VGMTGGW; -.
DR OrthoDB; 981397at2759; -.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR Genevisible; Q6L8F9; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0071577; P:zinc ion transmembrane transport; IBA:GO_Central.
DR InterPro; IPR003689; ZIP.
DR InterPro; IPR004698; Zn/Fe_permease_fun/pln.
DR Pfam; PF02535; Zip; 1.
DR TIGRFAMs; TIGR00820; zip; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Ion transport; Membrane; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport.
FT SIGNAL 1..?
FT /evidence="ECO:0000255"
FT CHAIN ?..395
FT /note="Zinc transporter 6"
FT /id="PRO_0000398330"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 55..63
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 85..104
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 126..241
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 263..269
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 291..300
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 322..333
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 334..354
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 355..374
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 375..395
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 132..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 395 AA; 41326 MW; FF1C50BCEC0AAD33 CRC64;
MSGTGCFPAG EMAAVARVCR DGAAAARLKT GSLLAILVAS AVGICLPVAL TGAFRGKAGY
ARGLLLVKCY AAGVILSTSL VHVLPDAHAA LADCAVATRR PWRDFPFAGL FSLVGALLAL
LVDLSASSHL EAHGHHQHAE EGESPPPPPP THQPYAPIPT TKKSPVFELS GEMSPKKRAH
SDDTDRDDVA LFGAKSAVRS DEVVVAPRVG CHGHHDVVEV GEEGGGGEEE EARRKQKMVS
KVLEIGIVFH SVIIGVTMGM SQDVCAIRPL VVALSFHQVF EGMGLGGCIA QAGFGIATVG
YMCVMFSVTT PLGILLGMAI FHMTGYDDSS PNALIIEGLL GSLSSGILVY MALVDLISLD
FFHNKMMSSS NKLKKVSYVA LVLGSASMSI LALWA
