ZIP7_ARATH
ID ZIP7_ARATH Reviewed; 365 AA.
AC Q8W246; Q6DBB4;
DT 26-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Zinc transporter 7;
DE AltName: Full=ZRT/IRT-like protein 7;
DE Flags: Precursor;
GN Name=ZIP7; OrderedLocusNames=At2g04032; ORFNames=F3C11.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11500563; DOI=10.1104/pp.126.4.1646;
RA Maeser P., Thomine S., Schroeder J.I., Ward J.M., Hirschi K., Sze H.,
RA Talke I.N., Amtmann A., Maathuis F.J.M., Sanders D., Harper J.F.,
RA Tchieu J., Gribskov M., Persans M.W., Salt D.E., Kim S.A., Guerinot M.L.;
RT "Phylogenetic relationships within cation transporter families of
RT Arabidopsis.";
RL Plant Physiol. 126:1646-1667(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably mediates zinc uptake from the rhizosphere.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000305}.
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DR EMBL; AF369911; AAL38434.1; -; Genomic_DNA.
DR EMBL; AC007167; AAM15429.1; -; Genomic_DNA.
DR EMBL; AC007178; AAM15439.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05780.1; -; Genomic_DNA.
DR EMBL; BT015108; AAT71980.1; -; mRNA.
DR RefSeq; NP_178488.1; NM_126440.3.
DR AlphaFoldDB; Q8W246; -.
DR STRING; 3702.AT2G04032.1; -.
DR PaxDb; Q8W246; -.
DR PRIDE; Q8W246; -.
DR EnsemblPlants; AT2G04032.1; AT2G04032.1; AT2G04032.
DR GeneID; 814931; -.
DR Gramene; AT2G04032.1; AT2G04032.1; AT2G04032.
DR KEGG; ath:AT2G04032; -.
DR Araport; AT2G04032; -.
DR TAIR; locus:2827434; AT2G04032.
DR eggNOG; KOG1558; Eukaryota.
DR HOGENOM; CLU_027089_3_0_1; -.
DR InParanoid; Q8W246; -.
DR OMA; DTAMAKE; -.
DR OrthoDB; 981397at2759; -.
DR PhylomeDB; Q8W246; -.
DR PRO; PR:Q8W246; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8W246; baseline and differential.
DR Genevisible; Q8W246; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0071577; P:zinc ion transmembrane transport; IBA:GO_Central.
DR InterPro; IPR003689; ZIP.
DR InterPro; IPR004698; Zn/Fe_permease_fun/pln.
DR Pfam; PF02535; Zip; 1.
DR TIGRFAMs; TIGR00820; zip; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Ion transport; Membrane; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..365
FT /note="Zinc transporter 7"
FT /id="PRO_0000041645"
FT TOPO_DOM 27..56
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 78..90
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 112..129
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 151..210
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 232..242
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 264..272
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 294..304
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 326..344
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 365 AA; 39378 MW; 8AC487DA9B664BA8 CRC64;
MAYSKACYKL TTITILLLSF TLPSLAGNAE NADVSECKAE SGDLSCHNNK EAQKLKIIAI
PSILVASMIG VSLPLFSRSI PALGPDREMS VIVKTLASGV ILATGFMHVL PDSFDDLTSK
CLPEDPWQKF PFATFITMIS ALLVLMIESF AMCAYARRTS KREGEVVPLE NGSNSVDTQN
DIQTLENGSS YVEKQEKVNE DKTSELLRNK VIAQILELGI VVHSVVIGLA MGASDNKCTV
QSLIAALCFH QLFEGMGLGG SILQAQFKSK TNWTMVFFFS VTTPFGIVLG MAIQKIYDET
SPTALIVVGV LNACSAGLLI YMALVNLLAH EFFGPKIQGN IKLHVLGYVA TFTGAAGMSL
MAKWA
