CC190_MOUSE
ID CC190_MOUSE Reviewed; 288 AA.
AC Q3URK1;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Coiled-coil domain-containing protein 190;
GN Name=Ccdc190;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Spinal cord;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- CAUTION: It is uncertain whether Met-1 or Met-5 is the initiator.
CC {ECO:0000305}.
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DR EMBL; AK141447; BAE24687.1; -; mRNA.
DR CCDS; CCDS15466.1; -.
DR RefSeq; NP_001028357.1; NM_001033185.2.
DR AlphaFoldDB; Q3URK1; -.
DR SMR; Q3URK1; -.
DR STRING; 10090.ENSMUSP00000091908; -.
DR PhosphoSitePlus; Q3URK1; -.
DR MaxQB; Q3URK1; -.
DR PaxDb; Q3URK1; -.
DR PRIDE; Q3URK1; -.
DR ProteomicsDB; 281490; -.
DR Antibodypedia; 34325; 93 antibodies from 15 providers.
DR Ensembl; ENSMUST00000094348; ENSMUSP00000091908; ENSMUSG00000070532.
DR GeneID; 78465; -.
DR KEGG; mmu:78465; -.
DR UCSC; uc007dlo.1; mouse.
DR CTD; 339512; -.
DR MGI; MGI:1925715; Ccdc190.
DR VEuPathDB; HostDB:ENSMUSG00000070532; -.
DR eggNOG; ENOG502SAE4; Eukaryota.
DR GeneTree; ENSGT00390000014067; -.
DR InParanoid; Q3URK1; -.
DR OMA; KVRNAHY; -.
DR PhylomeDB; Q3URK1; -.
DR TreeFam; TF338067; -.
DR BioGRID-ORCS; 78465; 1 hit in 39 CRISPR screens.
DR PRO; PR:Q3URK1; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q3URK1; protein.
DR Bgee; ENSMUSG00000070532; Expressed in hypothalamus and 30 other tissues.
DR ExpressionAtlas; Q3URK1; baseline and differential.
DR InterPro; IPR031525; CC190.
DR PANTHER; PTHR36871; PTHR36871; 1.
DR Pfam; PF15768; CC190; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..288
FT /note="Coiled-coil domain-containing protein 190"
FT /id="PRO_0000274499"
FT REGION 141..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 16..69
FT /evidence="ECO:0000255"
FT COMPBIAS 176..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 288 AA; 32592 MW; 3121B6EC9944CAA7 CRC64;
MDRSMVKGPL YKQFDLERKS ARQAEARLSL RLQRLEIICL YHVKSLAREQ RQLQKELQRL
QQDIIKKRFS SYVGHEIQKR SKDVVTFLPP TGQRHAVPEP KIRTLKNSVT QEVKTKIPVP
SLHDPVLKDT LRSQEHLLSH GERTSCFKEG SPQGQEGEPT NPLKGVDPSK DVSVPCHDQE
LSTNKTEDSG VSSQDGERGS APANETRSEN ASQKPRGDAD VQNSPSSVDY AGSFKDERTK
PSFLELFEKA KNAHYVRHRV PPESERLLSI GEIFGHKHYS LPRTGETL
