CC191_MACFA
ID CC191_MACFA Reviewed; 935 AA.
AC Q95KD7; Q95JP7; Q95LX1;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 48.
DE RecName: Full=Coiled-coil domain-containing protein 191;
GN Name=CCDC191; ORFNames=QflA-14927, QtsA-14717, QtsA-16413;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Frontal cortex, and Testis;
RX PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA Terao K., Sugano S., Hashimoto K.;
RT "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT the human genome sequence.";
RL BMC Genomics 3:36-36(2002).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q95KD7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q95KD7-2; Sequence=VSP_029097;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB64463.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAB64463.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
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DR EMBL; AB062941; BAB60732.1; -; mRNA.
DR EMBL; AB070134; BAB63079.1; -; mRNA.
DR EMBL; AB071070; BAB64463.1; ALT_SEQ; mRNA.
DR RefSeq; NP_001270951.1; NM_001284022.1. [Q95KD7-1]
DR AlphaFoldDB; Q95KD7; -.
DR STRING; 9541.XP_005548165.1; -.
DR PRIDE; Q95KD7; -.
DR GeneID; 102124924; -.
DR CTD; 57577; -.
DR eggNOG; ENOG502QS57; Eukaryota.
DR Proteomes; UP000233100; Unplaced.
DR InterPro; IPR026174; CC191.
DR PANTHER; PTHR22028:SF5; PTHR22028:SF5; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..935
FT /note="Coiled-coil domain-containing protein 191"
FT /id="PRO_0000309222"
FT REGION 596..661
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 189..324
FT /evidence="ECO:0000255"
FT COILED 366..438
FT /evidence="ECO:0000255"
FT COILED 554..589
FT /evidence="ECO:0000255"
FT COILED 660..740
FT /evidence="ECO:0000255"
FT COMPBIAS 621..638
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 246..611
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12498619"
FT /id="VSP_029097"
FT CONFLICT 318
FT /note="I -> T (in Ref. 1; BAB64463)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 935 AA; 110332 MW; 1A3EE790789D4F18 CRC64;
MLMAPQGRSS SKKRMGLNRW KRFTRKPSPQ HAFGPDNVEH WIKRVEKASE FAVSNAFFTR
NSDLPRSPWG QITDWKTSEQ IEDHDEIYAE AQELVNDWLD SKLKQELASD EEGDAKNTVS
SVSLVPEAND HLKYDKFDDL CGYLEEEEES TTVQKFIDHL LHKNVVDSAV MEDLGRKENQ
DKKQQKDPRL TMEMRHKQVK ENRLRREKEL EYQRIQKTLK KSAFLEAQCL VQEEKKRKAL
EAKKEEEEIQ REMVKLRREI IERRRTVKEA WKIEKKRQEE NSQNSSEKLM FQSTHILLDE
EKMAKERKRK LKELLIQIFK ENQQCQKRYF SAWHKLILDH RIKLGKAGTL SDWKIQLKVL
RAWRDYTRSQ KLQRETQALE NDLREENRKQ QLAAEHNRKQ VLRHCFTEWQ HWCGAELLKR
ELALTKEENR KKMDALLKAA SLGKLSASES SGISLPEEAT AVVGPPVRNG QVTAVPPLWE
KPPLGSSDCM LSPPLGRTTG NLQGSLQNVP LSAPGNKQHK TLGVEPPQLP GSNETLRTTS
QKAEPLCLGH FHSRHVFQQQ LIEKQKKKLQ EQQKTILELK KNQRLAEAQW AAEHASAVTD
TQSHLLSKPR GEEEPRTCQM LVNSPVASPG TEGSRSDSRN CLSGRKRKPK QLMTPHPILK
AMEERAIQRA ERRRILAEKK KKQEEEKLAQ LKAQEEERQK REAEEKEAQL ERKREEKRLK
KMKELEKQKR IKRNQQLEAI AKEHYEGVLL RKKGLEPWKI LRMQSKQNVQ VAEEHYCLFL
QRKYLLTWFQ CSQESLARKM AQADQFYSQI LLKRVIRSWL QYMTDLQEEV RKFCVRFLQK
KIFRAWFNMV REVKIDSRGK HEIAAEHSDR RILWITFRTW KKFVKFMKEE RVKEERRQQL
RRKVVEILPD FQVPGSDHEL YQQSDTWSLS KTSLL