ID   CC194_HUMAN             Reviewed;         234 AA.
AC   A0A1B0GVG4;
DT   27-SEP-2017, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2016, sequence version 1.
DT   03-AUG-2022, entry version 24.
DE   RecName: Full=Coiled-coil domain-containing protein 194 {ECO:0000305};
DE   Flags: Precursor;
GN   Name=CCDC194 {ECO:0000312|HGNC:HGNC:53438};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA   Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA   Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA   Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA   Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA   Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA   Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA   Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA   Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA   McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA   Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA   Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA   She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA   Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC010319; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A1B0GVG4; -.
DR   SMR; A0A1B0GVG4; -.
DR   MetOSite; A0A1B0GVG4; -.
DR   BioMuta; CCDC194; -.
DR   MassIVE; A0A1B0GVG4; -.
DR   PeptideAtlas; A0A1B0GVG4; -.
DR   Ensembl; ENST00000636079.1; ENSP00000490504.1; ENSG00000269720.2.
DR   MANE-Select; ENST00000636079.2; ENSP00000490504.1; NM_001395222.1; NP_001382151.1.
DR   GeneCards; CCDC194; -.
DR   HGNC; HGNC:53438; CCDC194.
DR   HPA; ENSG00000269720; Group enriched (brain, ovary).
DR   neXtProt; NX_A0A1B0GVG4; -.
DR   OpenTargets; ENSG00000269720; -.
DR   VEuPathDB; HostDB:ENSG00000269720; -.
DR   GeneTree; ENSGT00850000133633; -.
DR   OMA; MTLKTEM; -.
DR   Pharos; A0A1B0GVG4; Tdark.
DR   PRO; PR:A0A1B0GVG4; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   RNAct; A0A1B0GVG4; protein.
DR   Bgee; ENSG00000269720; Expressed in left ovary and 84 other tissues.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome; Signal.
FT   SIGNAL          1..42
FT                   /evidence="ECO:0000255"
FT   CHAIN           43..234
FT                   /note="Coiled-coil domain-containing protein 194"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000441407"
FT   REGION          44..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          187..234
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          66..163
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   234 AA;  24954 MW;  B6DB1428E65CD7E7 CRC64;
     MAEPGPEPGR AWRVLALCGV AVFLAAAAAG GALVAWNLAA SAARGPRCPE PGANATAPPG
     DPPPGVDDLR RRLAEAAERE EALARQLDQA ESIRHELEKA LKACEGRQSR LQTQLTTLKI
     EMDEAKAQGT QMGAENGALT EALARWEAAA TESTRRLDEA LRRAGVAEAE GEACAAREAA
     LRERLNVLEA EMSPQRRVPR PRPRSGSRPR PSPRSRSRSG PSGGCRRPAR RARG