ID   ZMAT3_BOVIN             Reviewed;         289 AA.
AC   Q0IIC4;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Zinc finger matrin-type protein 3;
GN   Name=ZMAT3 {ECO:0000250|UniProtKB:Q9HA38};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1] {ECO:0000312|EMBL:AAI22711.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus {ECO:0000312|EMBL:AAI22711.1};
RC   TISSUE=Liver {ECO:0000312|EMBL:AAI22711.1};
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a bona fide target gene of p53/TP53. May play a role
CC       in the TP53-dependent growth regulatory pathway. May contribute to
CC       TP53-mediated apoptosis by regulation of TP53 expression and
CC       translocation to the nucleus and nucleolus (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with dsRNA. {ECO:0000250|UniProtKB:Q9HA38}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O08781}. Nucleus,
CC       nucleolus {ECO:0000250|UniProtKB:O08781}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC122710; AAI22711.1; -; mRNA.
DR   RefSeq; NP_001069576.1; NM_001076108.1.
DR   RefSeq; XP_005201717.1; XM_005201660.3.
DR   AlphaFoldDB; Q0IIC4; -.
DR   SMR; Q0IIC4; -.
DR   STRING; 9913.ENSBTAP00000016535; -.
DR   PaxDb; Q0IIC4; -.
DR   PRIDE; Q0IIC4; -.
DR   Ensembl; ENSBTAT00000016535; ENSBTAP00000016535; ENSBTAG00000012463.
DR   Ensembl; ENSBTAT00000084595; ENSBTAP00000059046; ENSBTAG00000012463.
DR   GeneID; 538512; -.
DR   KEGG; bta:538512; -.
DR   CTD; 64393; -.
DR   VEuPathDB; HostDB:ENSBTAG00000012463; -.
DR   VGNC; VGNC:37192; ZMAT3.
DR   eggNOG; ENOG502QW4K; Eukaryota.
DR   GeneTree; ENSGT00730000111202; -.
DR   HOGENOM; CLU_051920_1_0_1; -.
DR   InParanoid; Q0IIC4; -.
DR   OMA; QAHYRGK; -.
DR   OrthoDB; 1565630at2759; -.
DR   TreeFam; TF350019; -.
DR   Proteomes; UP000009136; Chromosome 1.
DR   Bgee; ENSBTAG00000012463; Expressed in occipital lobe and 95 other tissues.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR   InterPro; IPR022755; Znf_C2H2_jaz.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF12171; zf-C2H2_jaz; 1.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   SMART; SM00451; ZnF_U1; 3.
DR   SUPFAM; SSF57667; SSF57667; 3.
PE   2: Evidence at transcript level;
KW   Apoptosis; DNA damage; Growth regulation; Metal-binding; Nucleus;
KW   Protein transport; Reference proteome; Repeat; RNA-binding; Translocation;
KW   Transport; Zinc; Zinc-finger.
FT   CHAIN           1..289
FT                   /note="Zinc finger matrin-type protein 3"
FT                   /id="PRO_0000310778"
FT   ZN_FING         70..100
FT                   /note="Matrin-type 1"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         147..177
FT                   /note="Matrin-type 2"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         246..276
FT                   /note="Matrin-type 3"
FT                   /evidence="ECO:0000255"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          180..200
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   289 AA;  31829 MW;  69F6E9915CB11FBD CRC64;
     MILLQHAGLP PPKRPSSSPP MSVAARSTGA LQLPPQKPFG QEASLPLAGE EEPPKGGEQD
     TALEELCKPL YCKLCNVTLN SAQQAQAHYQ GKNHGKKLRN YYAANSCPPP ARMSNAVEAV
     AAPAVSVPPQ MGSFKPGGRV ILATENDYCK LCDASFSSPA VAQAHYQGKN HAKRLRLAEA
     QSNSFSDSSE VGQRRTRKEG NEYKMMPNRR NMYAVQNNSA GPYFNPRSRQ RIPRDLAMCV
     TPSGQFYCSM CNVGAGEEVE FRQHLESKQH KSKVSEQRYR NEMENLGYV