ZMAT5_MOUSE
ID ZMAT5_MOUSE Reviewed; 170 AA.
AC Q9CQR5;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Zinc finger matrin-type protein 5;
DE AltName: Full=U11/U12 small nuclear ribonucleoprotein 20 kDa protein;
DE Short=U11/U12 snRNP 20 kDa protein;
GN Name=Zmat5; Synonyms=D11Bwg1548e;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Pancreas;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Colon;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBUNIT: Component of the U11/U12 snRNPs that are part of the U12-type
CC spliceosome. Not found in the major spliceosome (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR EMBL; AK003361; BAB22736.1; -; mRNA.
DR EMBL; AK007565; BAB25111.1; -; mRNA.
DR EMBL; AK012098; BAB28029.1; -; mRNA.
DR EMBL; AK013415; BAB28843.1; -; mRNA.
DR EMBL; AL606521; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC031796; AAH31796.1; -; mRNA.
DR CCDS; CCDS24389.1; -.
DR RefSeq; NP_080291.1; NM_026015.2.
DR RefSeq; XP_006514849.1; XM_006514786.1.
DR RefSeq; XP_006514850.1; XM_006514787.1.
DR AlphaFoldDB; Q9CQR5; -.
DR SMR; Q9CQR5; -.
DR BioGRID; 211996; 1.
DR STRING; 10090.ENSMUSP00000009220; -.
DR PhosphoSitePlus; Q9CQR5; -.
DR EPD; Q9CQR5; -.
DR MaxQB; Q9CQR5; -.
DR PaxDb; Q9CQR5; -.
DR PeptideAtlas; Q9CQR5; -.
DR PRIDE; Q9CQR5; -.
DR ProteomicsDB; 302064; -.
DR Antibodypedia; 330; 60 antibodies from 13 providers.
DR Ensembl; ENSMUST00000009220; ENSMUSP00000009220; ENSMUSG00000009076.
DR GeneID; 67178; -.
DR KEGG; mmu:67178; -.
DR UCSC; uc007hvc.1; mouse.
DR CTD; 55954; -.
DR MGI; MGI:1914428; Zmat5.
DR VEuPathDB; HostDB:ENSMUSG00000009076; -.
DR eggNOG; KOG3454; Eukaryota.
DR GeneTree; ENSGT00390000009869; -.
DR HOGENOM; CLU_100385_1_0_1; -.
DR InParanoid; Q9CQR5; -.
DR OMA; WPPIQEL; -.
DR OrthoDB; 1541869at2759; -.
DR PhylomeDB; Q9CQR5; -.
DR TreeFam; TF332784; -.
DR Reactome; R-MMU-72165; mRNA Splicing - Minor Pathway.
DR BioGRID-ORCS; 67178; 18 hits in 71 CRISPR screens.
DR ChiTaRS; Zmat5; mouse.
DR PRO; PR:Q9CQR5; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q9CQR5; protein.
DR Bgee; ENSMUSG00000009076; Expressed in morula and 177 other tissues.
DR Genevisible; Q9CQR5; MM.
DR GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR GO; GO:0005689; C:U12-type spliceosomal complex; ISS:HGNC-UCL.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR013085; U1-CZ_Znf_C2H2.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR Pfam; PF00642; zf-CCCH; 1.
DR Pfam; PF06220; zf-U1; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF57667; SSF57667; 1.
DR SUPFAM; SSF90229; SSF90229; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW Spliceosome; Zinc; Zinc-finger.
FT CHAIN 1..170
FT /note="Zinc finger matrin-type protein 5"
FT /id="PRO_0000254115"
FT ZN_FING 51..79
FT /note="C3H1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
SQ SEQUENCE 170 AA; 19886 MW; 66D78D91F28C4A70 CRC64;
MGKRYFCDYC DRSFQDNLHN RKKHLNGLQH LKAKKVWYDM FRDAAAILLD EQNKRPCRKF
LLTGQCDFGS NCRFSHMSEQ DLQELSVQVE EERRAREWPL ETAELPEGHL EDWLEKRAKR
LSSAPSSRAE PIRTTVFQYP VGWPPMQELP PSLRAPPPGG WSVLSKVQWG
