ZMY12_HUMAN
ID ZMY12_HUMAN Reviewed; 365 AA.
AC Q9H0C1; Q5VUS6; Q8TC87; Q96M51;
DT 10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 08-FEB-2011, sequence version 3.
DT 03-AUG-2022, entry version 157.
DE RecName: Full=Zinc finger MYND domain-containing protein 12;
GN Name=ZMYND12;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT LEU-316.
RC TISSUE=Testis;
RX PubMed=11230166; DOI=10.1101/gr.gr1547r;
RA Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S.,
RA Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J.,
RA Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W.,
RA Ottenwaelder B., Obermaier B., Tampe J., Heubner D., Wambutt R., Korn B.,
RA Klein M., Poustka A.;
RT "Towards a catalog of human genes and proteins: sequencing and analysis of
RT 500 novel complete protein coding human cDNAs.";
RL Genome Res. 11:422-435(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT LEU-316.
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C.,
RA Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J.,
RA Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J.,
RA Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y.,
RA Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J.,
RA Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S.,
RA Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K.,
RA Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R.,
RA Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M.,
RA Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J.,
RA Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W.,
RA McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S.,
RA Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M.,
RA White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H.,
RA Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E.,
RA Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G.,
RA Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT LEU-316.
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q9H0C1; Q9NYB9-2: ABI2; NbExp=5; IntAct=EBI-12030590, EBI-11096309;
CC Q9H0C1; P85298-4: ARHGAP8; NbExp=3; IntAct=EBI-12030590, EBI-9523517;
CC Q9H0C1; Q8IUR7-6: ARMC8; NbExp=3; IntAct=EBI-12030590, EBI-11942961;
CC Q9H0C1; O00327-8: ARNTL; NbExp=5; IntAct=EBI-12030590, EBI-11991546;
CC Q9H0C1; Q9NX04: C1orf109; NbExp=3; IntAct=EBI-12030590, EBI-8643161;
CC Q9H0C1; Q8IYX3: CCDC116; NbExp=3; IntAct=EBI-12030590, EBI-744311;
CC Q9H0C1; Q8N4L8: CCDC24; NbExp=3; IntAct=EBI-12030590, EBI-1104933;
CC Q9H0C1; Q9Y6H1: CHCHD2; NbExp=3; IntAct=EBI-12030590, EBI-2321769;
CC Q9H0C1; Q2TBE0: CWF19L2; NbExp=3; IntAct=EBI-12030590, EBI-5453285;
CC Q9H0C1; Q9NQL9: DMRT3; NbExp=3; IntAct=EBI-12030590, EBI-9679045;
CC Q9H0C1; Q03828: EVX2; NbExp=3; IntAct=EBI-12030590, EBI-17280301;
CC Q9H0C1; Q7L5A3: FAM214B; NbExp=3; IntAct=EBI-12030590, EBI-745689;
CC Q9H0C1; Q8WU58: FAM222B; NbExp=3; IntAct=EBI-12030590, EBI-2807642;
CC Q9H0C1; Q9Y247: FAM50B; NbExp=3; IntAct=EBI-12030590, EBI-742802;
CC Q9H0C1; Q86YD7: FAM90A1; NbExp=3; IntAct=EBI-12030590, EBI-6658203;
CC Q9H0C1; Q92917: GPKOW; NbExp=3; IntAct=EBI-12030590, EBI-746309;
CC Q9H0C1; O43708: GSTZ1; NbExp=3; IntAct=EBI-12030590, EBI-748043;
CC Q9H0C1; Q9GZV7: HAPLN2; NbExp=3; IntAct=EBI-12030590, EBI-11956675;
CC Q9H0C1; P56524-2: HDAC4; NbExp=3; IntAct=EBI-12030590, EBI-11953488;
CC Q9H0C1; P09067: HOXB5; NbExp=3; IntAct=EBI-12030590, EBI-3893317;
CC Q9H0C1; P31274: HOXC9; NbExp=3; IntAct=EBI-12030590, EBI-1779423;
CC Q9H0C1; O43593: HR; NbExp=3; IntAct=EBI-12030590, EBI-2880706;
CC Q9H0C1; Q9ULV5-2: HSF4; NbExp=3; IntAct=EBI-12030590, EBI-12056251;
CC Q9H0C1; Q12905: ILF2; NbExp=3; IntAct=EBI-12030590, EBI-357925;
CC Q9H0C1; Q0VD86: INCA1; NbExp=3; IntAct=EBI-12030590, EBI-6509505;
CC Q9H0C1; Q63ZY3: KANK2; NbExp=3; IntAct=EBI-12030590, EBI-2556193;
CC Q9H0C1; Q96BZ8: LENG1; NbExp=3; IntAct=EBI-12030590, EBI-726510;
CC Q9H0C1; P25791-3: LMO2; NbExp=3; IntAct=EBI-12030590, EBI-11959475;
CC Q9H0C1; P61968: LMO4; NbExp=3; IntAct=EBI-12030590, EBI-2798728;
CC Q9H0C1; Q9UI95: MAD2L2; NbExp=3; IntAct=EBI-12030590, EBI-77889;
CC Q9H0C1; Q8NEH6: MNS1; NbExp=3; IntAct=EBI-12030590, EBI-743811;
CC Q9H0C1; Q96BY2: MOAP1; NbExp=5; IntAct=EBI-12030590, EBI-739825;
CC Q9H0C1; A6NI15: MSGN1; NbExp=5; IntAct=EBI-12030590, EBI-11991020;
CC Q9H0C1; Q8IXL7-2: MSRB3; NbExp=3; IntAct=EBI-12030590, EBI-10699187;
CC Q9H0C1; Q15742: NAB2; NbExp=3; IntAct=EBI-12030590, EBI-8641936;
CC Q9H0C1; Q9BRQ3: NUDT22; NbExp=5; IntAct=EBI-12030590, EBI-10297093;
CC Q9H0C1; O60422: ONECUT3; NbExp=3; IntAct=EBI-12030590, EBI-17431136;
CC Q9H0C1; Q86TB9: PATL1; NbExp=3; IntAct=EBI-12030590, EBI-2562092;
CC Q9H0C1; Q9NRD5: PICK1; NbExp=3; IntAct=EBI-12030590, EBI-79165;
CC Q9H0C1; Q96HA1-2: POM121; NbExp=3; IntAct=EBI-12030590, EBI-11956563;
CC Q9H0C1; P78424: POU6F2; NbExp=3; IntAct=EBI-12030590, EBI-12029004;
CC Q9H0C1; Q6NYC8: PPP1R18; NbExp=3; IntAct=EBI-12030590, EBI-2557469;
CC Q9H0C1; Q7Z5V6-2: PPP1R32; NbExp=3; IntAct=EBI-12030590, EBI-12000762;
CC Q9H0C1; P54646: PRKAA2; NbExp=3; IntAct=EBI-12030590, EBI-1383852;
CC Q9H0C1; P0CG20: PRR35; NbExp=3; IntAct=EBI-12030590, EBI-11986293;
CC Q9H0C1; B1AHC3: PRR5-ARHGAP8; NbExp=3; IntAct=EBI-12030590, EBI-17437404;
CC Q9H0C1; Q6MZQ0: PRR5L; NbExp=3; IntAct=EBI-12030590, EBI-1567866;
CC Q9H0C1; P28062-2: PSMB8; NbExp=3; IntAct=EBI-12030590, EBI-372312;
CC Q9H0C1; P47897: QARS1; NbExp=5; IntAct=EBI-12030590, EBI-347462;
CC Q9H0C1; Q0D2K3: RIPPLY1; NbExp=3; IntAct=EBI-12030590, EBI-10226430;
CC Q9H0C1; Q9BVN2: RUSC1; NbExp=5; IntAct=EBI-12030590, EBI-6257312;
CC Q9H0C1; Q96NU1: SAMD11; NbExp=3; IntAct=EBI-12030590, EBI-14067109;
CC Q9H0C1; Q8IYX7: SAXO1; NbExp=3; IntAct=EBI-12030590, EBI-3957636;
CC Q9H0C1; Q9BWG6: SCNM1; NbExp=3; IntAct=EBI-12030590, EBI-748391;
CC Q9H0C1; O00560: SDCBP; NbExp=3; IntAct=EBI-12030590, EBI-727004;
CC Q9H0C1; Q9UDX3: SEC14L4; NbExp=3; IntAct=EBI-12030590, EBI-10320311;
CC Q9H0C1; Q9H788: SH2D4A; NbExp=3; IntAct=EBI-12030590, EBI-747035;
CC Q9H0C1; Q92529: SHC3; NbExp=3; IntAct=EBI-12030590, EBI-79084;
CC Q9H0C1; Q96GM5: SMARCD1; NbExp=3; IntAct=EBI-12030590, EBI-358489;
CC Q9H0C1; Q9H0W8: SMG9; NbExp=3; IntAct=EBI-12030590, EBI-2872322;
CC Q9H0C1; Q5JUK2: SOHLH1; NbExp=3; IntAct=EBI-12030590, EBI-12288855;
CC Q9H0C1; Q9NZD8: SPG21; NbExp=5; IntAct=EBI-12030590, EBI-742688;
CC Q9H0C1; Q7Z699: SPRED1; NbExp=3; IntAct=EBI-12030590, EBI-5235340;
CC Q9H0C1; Q7Z7C7: STRA8; NbExp=3; IntAct=EBI-12030590, EBI-12036261;
CC Q9H0C1; Q8WW24: TEKT4; NbExp=3; IntAct=EBI-12030590, EBI-750487;
CC Q9H0C1; Q96M29: TEKT5; NbExp=5; IntAct=EBI-12030590, EBI-10239812;
CC Q9H0C1; Q96N21: TEPSIN; NbExp=3; IntAct=EBI-12030590, EBI-11139477;
CC Q9H0C1; Q7Z6R9: TFAP2D; NbExp=3; IntAct=EBI-12030590, EBI-11952651;
CC Q9H0C1; Q96FV9: THOC1; NbExp=3; IntAct=EBI-12030590, EBI-1765605;
CC Q9H0C1; Q92748: THRSP; NbExp=3; IntAct=EBI-12030590, EBI-1749955;
CC Q9H0C1; Q08117-2: TLE5; NbExp=3; IntAct=EBI-12030590, EBI-11741437;
CC Q9H0C1; Q7Z6J9: TSEN54; NbExp=3; IntAct=EBI-12030590, EBI-2559824;
CC Q9H0C1; Q96PN8: TSSK3; NbExp=3; IntAct=EBI-12030590, EBI-3918381;
CC Q9H0C1; Q8TC83: TTC29; NbExp=5; IntAct=EBI-12030590, EBI-14887934;
CC Q9H0C1; Q99757: TXN2; NbExp=3; IntAct=EBI-12030590, EBI-2932492;
CC Q9H0C1; P19971: TYMP; NbExp=3; IntAct=EBI-12030590, EBI-2556931;
CC Q9H0C1; Q8IV45: UNC5CL; NbExp=5; IntAct=EBI-12030590, EBI-12238241;
CC Q9H0C1; Q14119: VEZF1; NbExp=3; IntAct=EBI-12030590, EBI-11980193;
CC Q9H0C1; A5D8V6: VPS37C; NbExp=3; IntAct=EBI-12030590, EBI-2559305;
CC Q9H0C1; Q9UQR1-2: ZNF148; NbExp=3; IntAct=EBI-12030590, EBI-11742222;
CC Q9H0C1; Q96IQ9: ZNF414; NbExp=3; IntAct=EBI-12030590, EBI-744257;
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DR EMBL; AL136858; CAB66792.1; -; mRNA.
DR EMBL; AK057384; BAB71461.1; -; mRNA.
DR EMBL; AL513331; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL445669; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC024186; AAH24186.1; -; mRNA.
DR CCDS; CCDS467.1; -.
DR RefSeq; NP_001139664.1; NM_001146192.1.
DR RefSeq; NP_115633.3; NM_032257.4.
DR AlphaFoldDB; Q9H0C1; -.
DR SMR; Q9H0C1; -.
DR BioGRID; 123951; 81.
DR IntAct; Q9H0C1; 81.
DR STRING; 9606.ENSP00000361646; -.
DR PhosphoSitePlus; Q9H0C1; -.
DR BioMuta; ZMYND12; -.
DR DMDM; 322510090; -.
DR MassIVE; Q9H0C1; -.
DR PaxDb; Q9H0C1; -.
DR PeptideAtlas; Q9H0C1; -.
DR PRIDE; Q9H0C1; -.
DR ProteomicsDB; 80250; -.
DR Antibodypedia; 32201; 50 antibodies from 16 providers.
DR DNASU; 84217; -.
DR Ensembl; ENST00000372565.8; ENSP00000361646.3; ENSG00000066185.13.
DR GeneID; 84217; -.
DR KEGG; hsa:84217; -.
DR MANE-Select; ENST00000372565.8; ENSP00000361646.3; NM_032257.5; NP_115633.3.
DR UCSC; uc001chj.4; human.
DR CTD; 84217; -.
DR GeneCards; ZMYND12; -.
DR HGNC; HGNC:21192; ZMYND12.
DR HPA; ENSG00000066185; Tissue enhanced (fallopian tube, testis).
DR neXtProt; NX_Q9H0C1; -.
DR OpenTargets; ENSG00000066185; -.
DR PharmGKB; PA134993145; -.
DR VEuPathDB; HostDB:ENSG00000066185; -.
DR eggNOG; ENOG502QSY3; Eukaryota.
DR GeneTree; ENSGT00390000004248; -.
DR HOGENOM; CLU_058444_1_1_1; -.
DR InParanoid; Q9H0C1; -.
DR OMA; FEGKHEA; -.
DR OrthoDB; 1025111at2759; -.
DR PhylomeDB; Q9H0C1; -.
DR TreeFam; TF328348; -.
DR PathwayCommons; Q9H0C1; -.
DR SignaLink; Q9H0C1; -.
DR BioGRID-ORCS; 84217; 16 hits in 1074 CRISPR screens.
DR ChiTaRS; ZMYND12; human.
DR GenomeRNAi; 84217; -.
DR Pharos; Q9H0C1; Tdark.
DR PRO; PR:Q9H0C1; -.
DR Proteomes; UP000005640; Chromosome 1.
DR RNAct; Q9H0C1; protein.
DR Bgee; ENSG00000066185; Expressed in sperm and 121 other tissues.
DR ExpressionAtlas; Q9H0C1; baseline and differential.
DR Genevisible; Q9H0C1; HS.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR002893; Znf_MYND.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF48452; SSF48452; 2.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 1: Evidence at protein level;
KW Metal-binding; Reference proteome; Repeat; TPR repeat; Zinc; Zinc-finger.
FT CHAIN 1..365
FT /note="Zinc finger MYND domain-containing protein 12"
FT /id="PRO_0000218316"
FT REPEAT 172..205
FT /note="TPR 1"
FT REPEAT 214..247
FT /note="TPR 2"
FT ZN_FING 17..54
FT /note="MYND-type; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 17
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 20
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 28
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 31
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 37
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 41
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 50
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 54
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT VARIANT 316
FT /note="F -> L (in dbSNP:rs1034268)"
FT /evidence="ECO:0000269|PubMed:11230166,
FT ECO:0000269|PubMed:14702039, ECO:0000269|PubMed:15489334"
FT /id="VAR_018425"
FT CONFLICT 134
FT /note="L -> P (in Ref. 1; CAB66792)"
FT /evidence="ECO:0000305"
FT CONFLICT 166
FT /note="C -> Y (in Ref. 2; BAB71461)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 365 AA; 41818 MW; 3974C5C55D0A2302 CRC64;
MNVIYPLAVP KGRRLCCEVC EAPAERVCAA CTVTYYCGVV HQKADWDSIH EKICQLLIPL
RTSMPFYNSE EERQHGLQQL QQRQKYLIEF CYTIAQKYLF EGKHEDAVPA ALQSLRFRVK
LYGLSSVELV PAYLLLAEAS LGLGRIVQAE EYLFQAQWTV LKSTDCSNAT HSLLHRNLGL
LYIAKKNYEE ARYHLANDIY FASCAFGTED IRTSGGYFHL ANIFYDLKKL DLADTLYTKV
SEIWHAYLNN HYQVLSQAHI QQMDLLGKLF ENDTGLDEAQ EAEAIRILTS ILNIRESTSD
KAPQKTIFVL KILVMFYYLM MNSSKAQEYG MRALSLAKEQ QLDVHEQSTI QELLSLISTE
DHPIT
