ID   ZMY19_RAT               Reviewed;         227 AA.
AC   Q7TSV3;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Zinc finger MYND domain-containing protein 19;
DE   AltName: Full=Melanin-concentrating hormone receptor 1-interacting zinc finger protein;
DE            Short=MCH-R1-interacting zinc finger protein;
GN   Name=Zmynd19; Synonyms=Mizip;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Wistar; TISSUE=Brain;
RX   PubMed=12208518; DOI=10.1016/s0014-5793(02)03115-0;
RA   Baechner D., Kreienkamp H.-J., Richter D.;
RT   "MIZIP, a highly conserved, vertebrate specific melanin-concentrating
RT   hormone receptor 1 interacting zinc-finger protein.";
RL   FEBS Lett. 526:124-128(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May be involved as a regulatory molecule in GPR24/MCH-R1
CC       signaling.
CC   -!- SUBUNIT: Interacts with GPR24/MCH-R1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
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DR   EMBL; AJ488144; CAD32374.1; -; mRNA.
DR   EMBL; BC088093; AAH88093.1; -; mRNA.
DR   RefSeq; NP_942065.1; NM_198770.2.
DR   AlphaFoldDB; Q7TSV3; -.
DR   SMR; Q7TSV3; -.
DR   STRING; 10116.ENSRNOP00000010270; -.
DR   PaxDb; Q7TSV3; -.
DR   Ensembl; ENSRNOT00000010270; ENSRNOP00000010270; ENSRNOG00000007752.
DR   GeneID; 311791; -.
DR   KEGG; rno:311791; -.
DR   UCSC; RGD:735079; rat.
DR   CTD; 116225; -.
DR   RGD; 735079; Zmynd19.
DR   eggNOG; ENOG502QUSS; Eukaryota.
DR   GeneTree; ENSGT00940000153820; -.
DR   HOGENOM; CLU_084232_0_0_1; -.
DR   InParanoid; Q7TSV3; -.
DR   OMA; YAFEARV; -.
DR   OrthoDB; 1254383at2759; -.
DR   PhylomeDB; Q7TSV3; -.
DR   TreeFam; TF329209; -.
DR   PRO; PR:Q7TSV3; -.
DR   Proteomes; UP000002494; Chromosome 3.
DR   Bgee; ENSRNOG00000007752; Expressed in quadriceps femoris and 19 other tissues.
DR   Genevisible; Q7TSV3; RN.
DR   GO; GO:0005737; C:cytoplasm; ISO:RGD.
DR   GO; GO:0016020; C:membrane; ISO:RGD.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045202; C:synapse; ISO:RGD.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR044925; His-Me_finger_sf.
DR   InterPro; IPR003615; HNH_nuc.
DR   InterPro; IPR032978; ZMYND19.
DR   InterPro; IPR002893; Znf_MYND.
DR   PANTHER; PTHR46831; PTHR46831; 1.
DR   Pfam; PF13392; HNH_3; 1.
DR   Pfam; PF01753; zf-MYND; 1.
DR   SUPFAM; SSF54060; SSF54060; 1.
DR   PROSITE; PS01360; ZF_MYND_1; 1.
DR   PROSITE; PS50865; ZF_MYND_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Cytoplasm; Membrane; Metal-binding; Reference proteome;
KW   Zinc; Zinc-finger.
FT   CHAIN           1..227
FT                   /note="Zinc finger MYND domain-containing protein 19"
FT                   /id="PRO_0000218321"
FT   ZN_FING         174..212
FT                   /note="MYND-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT   BINDING         187
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT   BINDING         190
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT   BINDING         208
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT   BINDING         212
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
SQ   SEQUENCE   227 AA;  26433 MW;  906F0B51B670063A CRC64;
     MTDFKLGIVR LGRVAGKTKY TLIDEQDIPL VESYSFEARM EVDADGNGAK IFAYAFDKNR
     GRGSGRLLHE LLWERHRGGV APGFQVVHLN AVTVDNRLDN LQLVPWGWRP KAEETSSKQR
     EQSLYWLAIQ QLPTDPIEEQ FPVLNVTRYY NANGDVVEEE ENSCTYYECH YPPCTVIEKQ
     LREFNICGRC QVARYCGSQC QQKDWPAHKK HCRERKRPFQ HELEPER