CC50C_BOVIN
ID CC50C_BOVIN Reviewed; 343 AA.
AC Q2T9P5;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Cell cycle control protein 50C;
DE AltName: Full=Transmembrane protein 30C;
GN Name=TMEM30C; Synonyms=CDC50C;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CDC50/LEM3 family. {ECO:0000305}.
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DR EMBL; BC111328; AAI11329.1; -; mRNA.
DR RefSeq; NP_001033239.1; NM_001038150.2.
DR AlphaFoldDB; Q2T9P5; -.
DR SMR; Q2T9P5; -.
DR STRING; 9913.ENSBTAP00000018165; -.
DR PaxDb; Q2T9P5; -.
DR Ensembl; ENSBTAT00000018165; ENSBTAP00000018165; ENSBTAG00000013667.
DR Ensembl; ENSBTAT00000084003; ENSBTAP00000068724; ENSBTAG00000013667.
DR GeneID; 531379; -.
DR KEGG; bta:531379; -.
DR CTD; 71027; -.
DR VEuPathDB; HostDB:ENSBTAG00000013667; -.
DR VGNC; VGNC:108949; TMEM30C.
DR eggNOG; KOG2952; Eukaryota.
DR GeneTree; ENSGT00390000004660; -.
DR HOGENOM; CLU_025025_1_0_1; -.
DR InParanoid; Q2T9P5; -.
DR OMA; TARPPYW; -.
DR OrthoDB; 889671at2759; -.
DR TreeFam; TF300873; -.
DR Proteomes; UP000009136; Chromosome 1.
DR Bgee; ENSBTAG00000013667; Expressed in spermatid and 36 other tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0045332; P:phospholipid translocation; IBA:GO_Central.
DR InterPro; IPR005045; CDC50/LEM3_fam.
DR InterPro; IPR030353; TMEM30C.
DR PANTHER; PTHR10926; PTHR10926; 1.
DR PANTHER; PTHR10926:SF1; PTHR10926:SF1; 1.
DR Pfam; PF03381; CDC50; 1.
DR PIRSF; PIRSF015840; DUF284_TM_euk; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..343
FT /note="Cell cycle control protein 50C"
FT /id="PRO_0000292844"
FT TOPO_DOM 1..34
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 56..306
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 307..327
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 328..343
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 66
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 164
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 205
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 265
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 343 AA; 39022 MW; 44BC7B96623E39A8 CRC64;
MKRKCQDYES RLPDNTAVKQ QQLPAFRLQL TASEILSGFF AIGLFCLGMG IILLLSAKSI
KEVEINYTEK CATCAKLREE ATNFDKECNC SISFYLPQKM EGNVYLYYKL YGFYQNLYRY
ILSRSNIQLV GADVKDVRNC APFRTSDNGL PIAPCGAIAN SMFNDTIVLW YNFNSSTHIR
VPMVRTETAW WTDKYVKFQN PAFQNLSSAF AGTAKPPNWP KPVYELDEND PGNNGFINDD
FIVWMRTAAF PNFKKLYRRL HRIGNFTEGL PAGSYSFIIN YNFPVSRFQG QKAVVLSTLT
WSGGSSLFLA LAYLVTGAVT LLASFSMMAL HLKLKERKTF FLQ
