ID   ZN345_BOVIN             Reviewed;         487 AA.
AC   Q3SYV7;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Zinc finger protein 345;
GN   Name=ZNF345;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; BC103362; AAI03363.1; -; mRNA.
DR   RefSeq; NP_001030404.1; NM_001035327.1.
DR   AlphaFoldDB; Q3SYV7; -.
DR   SMR; Q3SYV7; -.
DR   PRIDE; Q3SYV7; -.
DR   Ensembl; ENSBTAT00000026567; ENSBTAP00000026567; ENSBTAG00000008902.
DR   GeneID; 518207; -.
DR   KEGG; bta:518207; -.
DR   CTD; 25850; -.
DR   VEuPathDB; HostDB:ENSBTAG00000008902; -.
DR   eggNOG; KOG1721; Eukaryota.
DR   GeneTree; ENSGT00940000163308; -.
DR   HOGENOM; CLU_002678_44_5_1; -.
DR   InParanoid; Q3SYV7; -.
DR   OMA; CELETMN; -.
DR   OrthoDB; 1318335at2759; -.
DR   Reactome; R-BTA-212436; Generic Transcription Pathway.
DR   Proteomes; UP000009136; Chromosome 18.
DR   Bgee; ENSBTAG00000008902; Expressed in oocyte and 102 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 12.
DR   SMART; SM00355; ZnF_C2H2; 15.
DR   SUPFAM; SSF57667; SSF57667; 8.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 15.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 15.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..487
FT                   /note="Zinc finger protein 345"
FT                   /id="PRO_0000244601"
FT   ZN_FING         62..84
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         90..112
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         118..140
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         146..168
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         174..196
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         202..224
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         230..252
FT                   /note="C2H2-type 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         258..280
FT                   /note="C2H2-type 8"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         286..308
FT                   /note="C2H2-type 9"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         314..336
FT                   /note="C2H2-type 10"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         342..364
FT                   /note="C2H2-type 11"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         370..392
FT                   /note="C2H2-type 12"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         398..420
FT                   /note="C2H2-type 13"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         426..448
FT                   /note="C2H2-type 14"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         454..476
FT                   /note="C2H2-type 15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ   SEQUENCE   487 AA;  55270 MW;  7362A22FB24C3F9F CRC64;
     MERLIKNSIA YSRFRGDWEC KSQFERKQES QEGHLSQMIF TPEDMPTFNT QHQRIHTDEK
     LLECKECGKD FSFVSVLIRH QRIHTGEKPY ECKECGKAFG SGANLAYHQR IHTGEKPYEC
     NECGKAFGSG SNLTHHQRIH TGEKPYECKE CGKAFSFGSG LIRHQIIHSG EKPYECKVCG
     KSFSFESALT RHHRIHTGEK PYECKDCGKA FGSGSNLTQH RRVHTGEKPY ECKGCGMAFS
     SGSALTRHQR IHTGEKPYIC NECGKAFSFG SALTRHQRIH TGEKPYVCKE CGKAFNSGSD
     LTQHQRIHTG EKPYECKECE KAFRSGSKLI QHQRMHTGEK PYECKECGKA FSSGSDLTQH
     QRIHTGEKPY ECKECGKAFA SGSKLIQHQL IHTGEKPYEC RECRKSFSSG SALNRHQRIH
     TGQKPYECKE CEKTFGTGST LTQHQRMHTA EKLYECKACG KALGRGSEIQ QHKKNHAGEK
     LCELETP