ID   ZN367_RAT               Reviewed;         340 AA.
AC   Q5U2Z0;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Zinc finger protein 367;
GN   Name=Znf367; Synonyms=Zfp367;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Transcriptional activator. May be involved in transcriptional
CC       activation of erythroid genes (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC085804; AAH85804.1; -; mRNA.
DR   RefSeq; NP_001012051.1; NM_001012051.1.
DR   AlphaFoldDB; Q5U2Z0; -.
DR   SMR; Q5U2Z0; -.
DR   STRING; 10116.ENSRNOP00000030325; -.
DR   PaxDb; Q5U2Z0; -.
DR   PRIDE; Q5U2Z0; -.
DR   Ensembl; ENSRNOT00000036287; ENSRNOP00000030325; ENSRNOG00000027234.
DR   GeneID; 306695; -.
DR   KEGG; rno:306695; -.
DR   UCSC; RGD:1307136; rat.
DR   CTD; 238673; -.
DR   RGD; 1307136; Zfp367.
DR   eggNOG; KOG1721; Eukaryota.
DR   GeneTree; ENSGT00670000098074; -.
DR   HOGENOM; CLU_068261_0_0_1; -.
DR   InParanoid; Q5U2Z0; -.
DR   OMA; NKHPHVI; -.
DR   OrthoDB; 1318335at2759; -.
DR   PhylomeDB; Q5U2Z0; -.
DR   TreeFam; TF321334; -.
DR   PRO; PR:Q5U2Z0; -.
DR   Proteomes; UP000002494; Chromosome 17.
DR   Bgee; ENSRNOG00000027234; Expressed in thymus and 19 other tissues.
DR   Genevisible; Q5U2Z0; RN.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; ISO:RGD.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISO:RGD.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; ISO:RGD.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   2: Evidence at transcript level;
KW   Activator; Coiled coil; DNA-binding; Metal-binding; Nucleus;
KW   Phosphoprotein; Reference proteome; Repeat; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..340
FT                   /note="Zinc finger protein 367"
FT                   /id="PRO_0000285299"
FT   ZN_FING         157..179
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         185..209
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          96..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          280..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          299..332
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        121..140
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         300
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q7RTV3"
SQ   SEQUENCE   340 AA;  37472 MW;  2EE7433FC103A31A CRC64;
     MIRGAPAPMA EPPPVIFCHD SPKRVLVSVI RTTPATPPCS SVGEPEPPPP LVPTSPGFSD
     FMVYPWRWGE NAHNVTLSPG AAGGVVSAGL PAATELPTLR GAPPSSASVA AVSGGEDEEE
     ASSPDSGHLK DGIRRGRPRA DTVRDLINEG EHSSSRIRCN ICNRVFPREK SLQAHKRTHT
     GERPYLCDYP DCGKAFVQSG QLKTHQRLHT GEKPFVCSEN GCLSRFTHAN RHCPKHPYAR
     LKREEPTDTL SKHQSTDNKA AAEWLAKYWE MREQRTPTLK GKLVQKADQE QQDPLEYLQS
     DEEDDEKSGA QRRLQEQRER LHGALALIEL ANLTGAPLRQ