ID   ZN395_XENLA             Reviewed;         498 AA.
AC   Q6DFC8;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Zinc finger protein 395;
GN   Name=znf395;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC       Note=May shuttle between nucleus and cytoplasm. {ECO:0000250}.
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DR   EMBL; BC076811; AAH76811.1; -; mRNA.
DR   RefSeq; NP_001086563.1; NM_001093094.1.
DR   AlphaFoldDB; Q6DFC8; -.
DR   SMR; Q6DFC8; -.
DR   DNASU; 446398; -.
DR   GeneID; 446398; -.
DR   KEGG; xla:446398; -.
DR   CTD; 446398; -.
DR   Xenbase; XB-GENE-1218962; znf395.S.
DR   OrthoDB; 915379at2759; -.
DR   Proteomes; UP000186698; Chromosome 5S.
DR   Bgee; 446398; Expressed in blastula and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR031940; DUF4772.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF15997; DUF4772; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..498
FT                   /note="Zinc finger protein 395"
FT                   /id="PRO_0000047562"
FT   ZN_FING         285..310
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          129..165
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          209..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           171..180
FT                   /note="Nuclear export signal"
FT                   /evidence="ECO:0000250"
FT   COMPBIAS        131..157
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        214..245
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   498 AA;  54317 MW;  433E496DFA09F858 CRC64;
     MASMLSKRLG KRSLLGARVC APTLSGDGML VDGQMSIQAE ISGGFGAGAL EGGYCKEFPE
     DGSCASAMSP TNRFKLYPGQ KVYITHNGKE YVGLVEQHNH VDDEVKLFVL ELGLHLCRKM
     EDVRLAETQK PLSSPIEQSL PTSPGATSTS AQRSVSRSID VPKRRSDAVE MDEMMAAMVL
     TSLSCSPIVQ SPPCTDSIPA PRVTCDLWKE GGDVSDSGSS TTSGHWSASS GVSTPSPPHT
     DASPKYTSEV FSASHVDEGF ETDPDPFLLD EPAPRKRKNS VKIMYKCLWP NCGKLLRSIV
     GIKRHVKTQH LGDGLDSDQR KREEDFYYTE VQMKEDPEAE PTPKSPSSAT APLLIQPVPA
     KPETHAIEVP SVESPLSSAL SQSAPGSFWH IQTDHAYQAL SSIQIPVSPH IFTSISWAAA
     SSTIPTLSPI RSRSLSFSEQ QQQAIKSHLI VASPPRPSNG NRKIRGEAKK CRKVYGIEHR
     DQWCTACRWK KACQRFLD