ID   CC69B_XENLA             Reviewed;         301 AA.
AC   Q08AV7;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 2.
DT   03-AUG-2022, entry version 33.
DE   RecName: Full=Coiled-coil domain-containing protein 69-B;
GN   Name=ccdc69-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as a scaffold to regulate the recruitment and
CC       assembly of spindle midzone components. {ECO:0000250|UniProtKB:A6NI79}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC       {ECO:0000250|UniProtKB:A6NI79}. Midbody {ECO:0000250|UniProtKB:A6NI79}.
CC       Note=During early anaphase, localizes along overlapping interpolar
CC       microtubules between the separating chromosomes. During late anaphase,
CC       localizes to the center of spindle midzone. Concentrated at the midbody
CC       during telophase. {ECO:0000250|UniProtKB:A6NI79}.
CC   -!- SIMILARITY: Belongs to the CCDC69 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI24991.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; BC124990; AAI24991.1; ALT_FRAME; mRNA.
DR   RefSeq; NP_001121321.1; NM_001127849.1.
DR   AlphaFoldDB; Q08AV7; -.
DR   SMR; Q08AV7; -.
DR   DNASU; 100158406; -.
DR   GeneID; 100158406; -.
DR   KEGG; xla:100158406; -.
DR   CTD; 100158406; -.
DR   OrthoDB; 1278490at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 100158406; Expressed in egg cell and 18 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR   GO; GO:0051233; C:spindle midzone; ISS:UniProtKB.
DR   GO; GO:0051255; P:spindle midzone assembly; ISS:UniProtKB.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Lipoprotein; Myristate;
KW   Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000255"
FT   CHAIN           2..301
FT                   /note="Coiled-coil domain-containing protein 69-B"
FT                   /id="PRO_0000328966"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          42..167
FT                   /evidence="ECO:0000255"
FT   COILED          213..281
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        28..42
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   301 AA;  35136 MW;  269C51D6FD4CB5A3 CRC64;
     MGSKTSKMCC PQLRKKKRQK AHKEGPSSQE LNDLNAKSQG PNELLQKIKE YEQEIRNILQ
     KHQEEKTALA DAHKADVEAR TLVLQAQAQK DRDAETVKLL SEQAATMKAE MEEMFAELQK
     SYEQEKSSLT EIHQQLTDAL QESVDELNSQ LASFREKMKR VEESILSQDY QRHIQDYGSP
     GQFWEKELQS LHFVIEMKSE LIREQDKRLQ RHKSTMERSL ELEERSRTLQ QENEALKVQT
     QKQGAITVRL SEELLSIQTT LEKQTHRCEQ LEREKEQNLY RAVIGDITQQ FSLQELPVMV
     L