ID   ZN414_RAT               Reviewed;         299 AA.
AC   Q5PPH4;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Zinc finger protein 414;
GN   Name=Znf414; Synonyms=Zfp414;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC087693; AAH87693.1; -; mRNA.
DR   RefSeq; NP_001009664.1; NM_001009664.1.
DR   AlphaFoldDB; Q5PPH4; -.
DR   STRING; 10116.ENSRNOP00000011094; -.
DR   PaxDb; Q5PPH4; -.
DR   GeneID; 299647; -.
DR   KEGG; rno:299647; -.
DR   UCSC; RGD:1308123; rat.
DR   CTD; 328801; -.
DR   RGD; 1308123; Zfp414.
DR   VEuPathDB; HostDB:ENSRNOG00000008378; -.
DR   eggNOG; KOG1721; Eukaryota.
DR   HOGENOM; CLU_049178_0_0_1; -.
DR   InParanoid; Q5PPH4; -.
DR   OMA; CSRRILW; -.
DR   OrthoDB; 943003at2759; -.
DR   PhylomeDB; Q5PPH4; -.
DR   TreeFam; TF337512; -.
DR   PRO; PR:Q5PPH4; -.
DR   Proteomes; UP000002494; Chromosome 7.
DR   Bgee; ENSRNOG00000008378; Expressed in testis and 20 other tissues.
DR   Genevisible; Q5PPH4; RN.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR039882; ZN414.
DR   InterPro; IPR031799; Znf-C2H2_ribbon.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR21695; PTHR21695; 1.
DR   Pfam; PF15909; zf-C2H2_8; 1.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..299
FT                   /note="Zinc finger protein 414"
FT                   /id="PRO_0000242165"
FT   ZN_FING         99..123
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         135..159
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         166..190
FT                   /note="C2H2-type 3; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          1..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          193..228
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          254..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..24
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..207
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        264..289
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   299 AA;  31967 MW;  0988FF9C3263345B CRC64;
     MEELSGPSSD TLATVESSSN EPDKEVASPD VAATATLSSV EEPGPNPTAT PPVWDRGGPL
     QQVACPVPDS CQTSSTTRGV GTNEDLRLPR RRPPPGKQIP CSSPGCSLSF PSVRDLAQHL
     RTHCPPTQSL EGKLFRCSAL SCTESFPSMQ ELVAHGKLHY KPNRYFKCEN CLLRFRTHRS
     LFKHLHVCID HGQNPAPPPP PALDKEPPVP ERPPESDPSS SLGLPFPLLE PFTSAPTGPF
     LPYLNPAPFG LSPPRLRPFL AATPGPPTSS TAIWKKSQGA TSSPRRPQGG SDAPSGACR