ZN474_BOVIN
ID ZN474_BOVIN Reviewed; 454 AA.
AC A6QQM4; Q32P70;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Zinc finger protein 474;
GN Name=ZNF474;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford;
RX PubMed=19390049; DOI=10.1126/science.1169588;
RG The bovine genome sequencing and analysis consortium;
RT "The genome sequence of taurine cattle: a window to ruminant biology and
RT evolution.";
RL Science 324:522-528(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=Crossbred X Angus, and Hereford; TISSUE=Hypothalamus, and Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=A6QQM4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=A6QQM4-2; Sequence=VSP_035630;
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DR EMBL; AAFC03049185; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC108236; AAI08237.1; -; mRNA.
DR EMBL; BC149901; AAI49902.1; -; mRNA.
DR RefSeq; NP_001032567.1; NM_001037490.1. [A6QQM4-2]
DR RefSeq; NP_001098482.1; NM_001105012.2. [A6QQM4-1]
DR AlphaFoldDB; A6QQM4; -.
DR STRING; 9913.ENSBTAP00000049829; -.
DR PaxDb; A6QQM4; -.
DR PRIDE; A6QQM4; -.
DR Ensembl; ENSBTAT00000026489; ENSBTAP00000026489; ENSBTAG00000019881. [A6QQM4-2]
DR GeneID; 781423; -.
DR KEGG; bta:781423; -.
DR VEuPathDB; HostDB:ENSBTAG00000019881; -.
DR eggNOG; ENOG502QWEF; Eukaryota.
DR GeneTree; ENSGT00530000064208; -.
DR HOGENOM; CLU_156078_0_0_1; -.
DR InParanoid; A6QQM4; -.
DR OMA; SQGLMVE; -.
DR OrthoDB; 778172at2759; -.
DR Proteomes; UP000009136; Chromosome 7.
DR Bgee; ENSBTAG00000019881; Expressed in semen and 62 other tissues.
DR ExpressionAtlas; A6QQM4; baseline.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR026319; ZC2HC1.
DR PANTHER; PTHR13555; PTHR13555; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..454
FT /note="Zinc finger protein 474"
FT /id="PRO_0000353098"
FT ZN_FING 164..187
FT /note="C2H2-type; degenerate"
FT REGION 48..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..346
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.2"
FT /id="VSP_035630"
SQ SEQUENCE 454 AA; 51182 MW; 7918FBF364124A1A CRC64;
MEREEEKRVS TLQQSFHHSK EPTFLINQAV LFGESHSSFL PEIERDNRGE KIKTNPRKNR
PGTVILSKQS SRRIMSGSQP RPPVIPSRRP GFRVCYICGR EFGSQSLGIH EPQCLEKWRV
ENSKLPKHLR RPEPSKPPPF SGSGSYSLQA ANEAAFQSSQ AQLLPCETCG RTFLPDRLLV
HQRSCKQKVE GPRAPSLDRS DDLAGLKKVS SGITTRPRTV ICYICGREFG TLSLPIHEPK
CLEKWKVEND RLPREFRQPL PQKPQPLLTG QPKHAGPRQG QLVSCPNCSQ TFAPDRLPVH
QRSCKAQPSG PKVQDLTLGS RGGLKESTNP KPQRNMAAPP VTDKPKMIRR PPTIVCYICG
REYGTKSIAI HEPQCLKKWH NENNLLPKEL RRPEPKKPEV RTITAKGFYD LDALNEAAWT
SAQSQLVPCN ICGRTFLPDR LIVHQRSCKP KVAK