ID   ZN512_MACFA             Reviewed;         565 AA.
AC   Q95JV5;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Zinc finger protein 512;
GN   Name=ZNF512; ORFNames=QtsA-11181;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA   Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA   Terao K., Sugano S., Hashimoto K.;
RT   "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT   the human genome sequence.";
RL   BMC Genomics 3:36-36(2002).
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; AB070073; BAB63018.1; -; mRNA.
DR   RefSeq; NP_001274582.1; NM_001287653.1.
DR   AlphaFoldDB; Q95JV5; -.
DR   STRING; 9541.XP_005576311.1; -.
DR   Ensembl; ENSMFAT00000069865; ENSMFAP00000019317; ENSMFAG00000032585.
DR   GeneID; 102142112; -.
DR   CTD; 84450; -.
DR   eggNOG; KOG1721; Eukaryota.
DR   GeneTree; ENSGT00940000158595; -.
DR   Proteomes; UP000233100; Chromosome 13.
DR   Bgee; ENSMFAG00000032585; Expressed in lymph node and 13 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 1.
DR   SMART; SM00355; ZnF_C2H2; 4.
DR   SUPFAM; SSF57667; SSF57667; 5.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   2: Evidence at transcript level;
KW   DNA-binding; Isopeptide bond; Metal-binding; Nucleus; Reference proteome;
KW   Repeat; Transcription; Transcription regulation; Ubl conjugation; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..565
FT                   /note="Zinc finger protein 512"
FT                   /id="PRO_0000047631"
FT   ZN_FING         196..219
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         286..309
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         405..429
FT                   /note="C2H2-type 3; atypical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         439..462
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          85..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          484..565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        96..118
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        518..537
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CROSSLNK        18
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q96ME7"
FT   CROSSLNK        83
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q96ME7"
FT   CROSSLNK        226
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q96ME7"
FT   CROSSLNK        332
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q96ME7"
SQ   SEQUENCE   565 AA;  64495 MW;  5C346681D1BE038D CRC64;
     MSSRLGAVPA TSGPTTFKQQ RSTRIVGAKN RTQCSIKDNS FQYTIPHDDS LSGSSSASSC
     EPVSDFPASF RKSTYWMKMR RIKPAATSHV EGSGGVSAKG KRKPRQEEDE DYREFPQKKH
     KLYGRKQRPK TQPNPKSQAR RIRKEPPVYA AGSLEEQWYL EIVDKGSVSC PTCQAVGRKT
     IEGLKKHMEN CKQEMFTCHH CGKQLRSLAG MKYHVMANHN SLPILKAGDE IDEPTERERL
     RTVLKRLGKL RCMRESCSSS FTSIMGYLYH VRKCGKGAAE LEKMTLKCHH CGKPYRSKAG
     LAYHLRSEHG PISFFPESGQ PECLKEMNLE SKSGGRVQRR SAKIAVYHLQ ELASAELAKE
     WPKRKVLQDL VPDDRKLKYT RPGLPTFSQE VLHKWKTDIK KYHRIQCPNQ GCEAVYSSVS
     GLKAHLGSCT LGNFVAGKYK CLLCQKEFVS ESGVKYHINS VHAEDWFVVN PTTTKSFEKL
     MKIKQRQQEE EKRRQQHRSR RSLRRRQQPG IELPETELSL RVGKDQRRNE ELVVSASCKE
     PEQEPVPAQF QKVKPPKTNH KRGRK