ZN526_BOVIN
ID ZN526_BOVIN Reviewed; 677 AA.
AC A6QR00;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Zinc finger protein 526;
GN Name=ZNF526;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal skin;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; BC150058; AAI50059.1; -; mRNA.
DR RefSeq; NP_001095467.1; NM_001101997.1.
DR AlphaFoldDB; A6QR00; -.
DR SMR; A6QR00; -.
DR STRING; 9913.ENSBTAP00000027659; -.
DR PaxDb; A6QR00; -.
DR PRIDE; A6QR00; -.
DR Ensembl; ENSBTAT00000027659; ENSBTAP00000027659; ENSBTAG00000020754.
DR GeneID; 514418; -.
DR KEGG; bta:514418; -.
DR CTD; 116115; -.
DR VEuPathDB; HostDB:ENSBTAG00000020754; -.
DR VGNC; VGNC:37297; ZNF526.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000162624; -.
DR HOGENOM; CLU_002678_24_3_1; -.
DR InParanoid; A6QR00; -.
DR OMA; CGDCPQH; -.
DR OrthoDB; 1318335at2759; -.
DR TreeFam; TF350791; -.
DR Proteomes; UP000009136; Chromosome 18.
DR Bgee; ENSBTAG00000020754; Expressed in laryngeal cartilage and 106 other tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF00096; zf-C2H2; 3.
DR SMART; SM00355; ZnF_C2H2; 13.
DR SUPFAM; SSF57667; SSF57667; 7.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 12.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 11.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..677
FT /note="Zinc finger protein 526"
FT /id="PRO_0000306874"
FT ZN_FING 57..79
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 109..131
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 141..164
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 198..220
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 304..326
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 331..353
FT /note="C2H2-type 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 359..381
FT /note="C2H2-type 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 387..408
FT /note="C2H2-type 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 449..472
FT /note="C2H2-type 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 479..501
FT /note="C2H2-type 10"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 507..529
FT /note="C2H2-type 11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 535..557
FT /note="C2H2-type 12"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 580..602
FT /note="C2H2-type 13"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT REGION 167..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 608..627
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..190
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..255
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..449
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..627
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 677 AA; 73935 MW; 3CBDA098870A6F9A CRC64;
MAEVVAEVAE VAEMPTQMSP RVMEMSAPIL GEKMELSTEL TEMTPGEAVA SSLFFQFMCS
ECGNLYNTLE EVLSHQEQHV PTVTEEEALT TQDTGLEPEL VPGTEEGPFQ CGECSQLILS
PRELLAHQDA HLRESASQIQ YQCGDCQELF PSPELWVAHR KAQHLSTAAA KPPVPPPLPP
VTPPPPPPAP LEVKMEPYEC PECSTLCTTP EEFLEHQGTH FDSLEKEEHN GLEEEEEDDE
DDNEETEEEE EAAAEVGDDA KGGDKSAAGQ AQGSGDGPPH CTSAGTRRRH RRASHGPASA
AHPFYCSQCQ RSFSSANRLL AHGRAHVGGT HECTTCSKVF KKAASLEQHL RLHRGEARYL
CVDCGRGFGT ELTLVAHRRA HTANPLHRCR CGKTFSNMTK FLYHRRTHAG KSGAPPSAAP
PTVASAVASL APAEPTPPPP APPTPPAQLP CPQCPKSFAS ASRLSRHRRA VHGPPERRHR
CGVCGKGFKK LVHVRNHLRT HTGERPFQCH ACGKTFASLA NLSRHQLTHT GVRPYQCLDC
GKRFTQSSNL QQHRRLHLRP VAFARAPRLP ITGLYNKSPY YCGTCGRWFR AMAGLRLHQR
VHAQARTLTL QPPRSPPPAP PPPPEPQQTI MCTELGETIA IIETSQPLAL ADTLQLCQAA
LGASEASGLL QLDTAFM
