ID   CC85C_XENLA             Reviewed;         390 AA.
AC   Q4V872;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 41.
DE   RecName: Full=Coiled-coil domain-containing protein 85C;
GN   Name=ccdc85c;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in cell-cell adhesion and epithelium
CC       development (By similarity). May play an important role in cortical
CC       development, especially in the maintenance of radial glia (By
CC       similarity). {ECO:0000250|UniProtKB:A6NKD9,
CC       ECO:0000250|UniProtKB:E9Q6B2}.
CC   -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC       {ECO:0000250|UniProtKB:E9Q6B2}. Cell junction, adherens junction
CC       {ECO:0000250|UniProtKB:A6NKD9}.
CC   -!- SIMILARITY: Belongs to the CCDC85 family. {ECO:0000305}.
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DR   EMBL; BC097515; AAH97515.1; -; mRNA.
DR   RefSeq; NP_001089440.1; NM_001095971.1.
DR   AlphaFoldDB; Q4V872; -.
DR   SMR; Q4V872; -.
DR   DNASU; 734490; -.
DR   GeneID; 734490; -.
DR   KEGG; xla:734490; -.
DR   CTD; 734490; -.
DR   Xenbase; XB-GENE-5853473; ccdc85c.S.
DR   OrthoDB; 1393196at2759; -.
DR   Proteomes; UP000186698; Chromosome 8S.
DR   Bgee; 734490; Expressed in camera-type eye and 17 other tissues.
DR   GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019359; CCDC85.
DR   PANTHER; PTHR13546; PTHR13546; 1.
DR   Pfam; PF10226; CCDC85; 1.
PE   2: Evidence at transcript level;
KW   Cell junction; Coiled coil; Developmental protein; Reference proteome;
KW   Tight junction.
FT   CHAIN           1..390
FT                   /note="Coiled-coil domain-containing protein 85C"
FT                   /id="PRO_0000345413"
FT   REGION          153..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          26..86
FT                   /evidence="ECO:0000255"
FT   COILED          116..146
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        158..193
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..223
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   390 AA;  43989 MW;  28DC238FBA8A67A8 CRC64;
     MAKHCQGAAA EDISAVSDEE LLRWSKEELI KRLRKVDNEK MSLMLEHGNM MKDVNRRLQL
     HLHEIRGLKD VNQKLQDESQ ELRELCCFLD DDRQKGKKLS REWQRFGRHS ATVVWKEVGT
     YQQKLKELEA KQESLVRDNL ELKEIILMLD EERNGPGSRS SIDSQNSLTN LNGGSGPRDV
     GDGSSTSSTG SAGSPDHHHH HHHIKTTENK AGTIRKSTDD LSVPPHHRSI PNGLNDSSTT
     YIRQLETRVK LLEDDNKLLS QHSTSGELRT LRKGLSPYHS ESQLSSLPQY QEPLQNGSAR
     VAPEVSSTAP AGYIPVVQKP EAVVHAMKVL EVHENLDRQI PDTYEEDLSE KEKAIVREMC
     NVVWRKLGDA ANSKPSIRQH LSGNQFKGPL