ZN567_BOVIN
ID ZN567_BOVIN Reviewed; 647 AA.
AC A2VDP4;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Zinc finger protein 567;
GN Name=ZNF567;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Basal ganglia;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; BC133337; AAI33338.1; -; mRNA.
DR RefSeq; NP_001075068.1; NM_001081599.1.
DR AlphaFoldDB; A2VDP4; -.
DR SMR; A2VDP4; -.
DR STRING; 9913.ENSBTAP00000018075; -.
DR PaxDb; A2VDP4; -.
DR PRIDE; A2VDP4; -.
DR GeneID; 532421; -.
DR KEGG; bta:532421; -.
DR CTD; 163081; -.
DR eggNOG; KOG1721; Eukaryota.
DR InParanoid; A2VDP4; -.
DR OrthoDB; 1318335at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 14.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 14.
DR SUPFAM; SSF109640; SSF109640; 1.
DR SUPFAM; SSF57667; SSF57667; 8.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 14.
PE 2: Evidence at transcript level;
KW DNA-binding; Isopeptide bond; Metal-binding; Nucleus; Reference proteome;
KW Repeat; Transcription; Transcription regulation; Ubl conjugation; Zinc;
KW Zinc-finger.
FT CHAIN 1..647
FT /note="Zinc finger protein 567"
FT /id="PRO_0000291554"
FT DOMAIN 32..77
FT /note="KRAB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00119"
FT ZN_FING 210..232
FT /note="C2H2-type 1; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 253..275
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 281..303
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 309..331
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 337..359
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 365..387
FT /note="C2H2-type 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 393..415
FT /note="C2H2-type 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 421..443
FT /note="C2H2-type 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 449..471
FT /note="C2H2-type 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 477..499
FT /note="C2H2-type 10"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 505..527
FT /note="C2H2-type 11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 533..555
FT /note="C2H2-type 12"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 561..583
FT /note="C2H2-type 13"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 589..611
FT /note="C2H2-type 14"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 617..639
FT /note="C2H2-type 15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT CROSSLNK 173
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8N184"
FT CROSSLNK 202
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8N184"
FT CROSSLNK 217
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8N184"
FT CROSSLNK 447
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8N184"
SQ SEQUENCE 647 AA; 75170 MW; 8EA213A72957E36B CRC64;
MAQGSVSFKD VTVDFSQEEW QHLDPAQKTL YMDVMLENYC HLISVGCHMT KPDVILKLER
GEEPWTSFKG HTCLEENWKA EDFLLKFKEQ QDKYSRSVIL INHKKLVNEN GSTCEKTLTL
SKNPINSKKL PPEYDTREKI LKNVSELIIS NLSPTRRRLS ECNGYGKSLL NTKPETAHSG
VKSHNQCGRT ISHNEKITQY HKMETPAQSF EYNDCEKAFL KRGGPVTHSR TYRRGNTSDY
NKRRRTTNIE KKHTCTECGK SFCRKSVLIL HQGIHTEEKP YQCHQCGNSF RRKSYLIDHQ
RTHTGEKPFV CNECGKSFRL KTALTDHQRT HTGEKSYECP QCRNAFRLKS HLIRHQRTHT
GEKPYECSDC GKSFRQKTTL SLHQRIHTGE KPYICKECGK SFHQKANLTV HQRTHTGEKP
YICNECGKSF SQKTTLALHE KTHNEEKPYI CNECGKSFPQ KTTLVAHQRT HTGEKSYECP
HCGKAFRMKS YLIDHHRTHT GEKPYECNEC GKSFSQKTNL NLHQRIHTGE KPYICNECGK
SFRQKATLTV HQKIHTGQKS YECPQCGKAF SRKSYLIHHQ RTHTGEKPYK CSECGKCFRQ
KTNLIVHQRT HTGEKPYICN ECGKSFSYKR NLIVHQRTHK GENMEMQ
