ZN571_PONAB
ID ZN571_PONAB Reviewed; 608 AA.
AC Q5R5Q6;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Zinc finger protein 571;
GN Name=ZNF571;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; CR860800; CAH92910.1; -; mRNA.
DR RefSeq; NP_001126710.1; NM_001133238.1.
DR AlphaFoldDB; Q5R5Q6; -.
DR SMR; Q5R5Q6; -.
DR STRING; 9601.ENSPPYP00000011102; -.
DR GeneID; 100173710; -.
DR KEGG; pon:100173710; -.
DR CTD; 51276; -.
DR eggNOG; KOG1721; Eukaryota.
DR InParanoid; Q5R5Q6; -.
DR OrthoDB; 1318335at2759; -.
DR Proteomes; UP000001595; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 13.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 16.
DR SUPFAM; SSF109640; SSF109640; 1.
DR SUPFAM; SSF57667; SSF57667; 9.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 16.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 17.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..608
FT /note="Zinc finger protein 571"
FT /id="PRO_0000047663"
FT DOMAIN 6..84
FT /note="KRAB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00119"
FT ZN_FING 138..160
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 163..188
FT /note="C2H2-type 2; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 194..216
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 222..244
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 250..272
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 278..300
FT /note="C2H2-type 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 306..328
FT /note="C2H2-type 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 334..356
FT /note="C2H2-type 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 362..384
FT /note="C2H2-type 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 390..412
FT /note="C2H2-type 10"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 418..440
FT /note="C2H2-type 11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 446..468
FT /note="C2H2-type 12"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 473..495
FT /note="C2H2-type 13"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 501..523
FT /note="C2H2-type 14"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 529..551
FT /note="C2H2-type 15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 557..579
FT /note="C2H2-type 16"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 585..607
FT /note="C2H2-type 17"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ SEQUENCE 608 AA; 70559 MW; 4A53806233A683D4 CRC64;
MPHLLVTFRD VAIDFTQEEW ECLDPAQRDL YRDVMLENYS NLISLDLESS CATKKLSPEK
EIYEMESLQW ENIGNLINHH LQYGLGDNME CKGNLEGQEA SQEGLYMCVK ITCEEKATES
HSTSSTFHRM IPTKEKLYKC KECRQGFSYL SCLIQHEKNH NIEKCSEVKK HRNTFSKKPS
YIQHQRIQTG EKPYECMECG KAFGRSSDLI QHQKIHTNEK PYQCNACGKA FIRGSQLTEH
QRVHTGEKPY ECKKCGKAFS YCSQYTLHQR IHSGEKPYEC KDCGKAFILG SQLTYHQRIH
SGEKPYECKE CGKAFILGSH LTYHQRVHTG EKPYICKECG KAFLCASQLN EHQRIHTGEK
PYECKECGKA FFRGSQLTYH LRVHSGERPY KCKECGKAFI SNSNLIQHQR IHTGEKPYKC
KECGKAFICG KQLSEHQRIH TGEKPFECKE CGKAFIRVAY LTQHEKIHGE KHYECKECGK
TFVRATQLTY HQRIHTGEKP YKCKECDKAF IYGSQLSEHQ RIHKGEKPYE CKQCGKAFIR
GSHLTEHLRT HTGEKPYECK ECGKAFSRGS ELTLHQRIHT GEKPYTCVQC GKDFRRPSQL
TQHTRLHN
