ID   ZN593_CAEEL             Reviewed;         128 AA.
AC   Q9U239;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Zinc finger protein 593 homolog;
GN   ORFNames=Y56A3A.18;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Involved in pre-60S ribosomal particles maturation by
CC       promoting the nuclear export of the 60S ribosome.
CC       {ECO:0000250|UniProtKB:Q08004}.
CC   -!- SUBUNIT: Associates with pre-60S ribosomal particles; released from the
CC       pre-60S particle very early in the cytoplasm.
CC       {ECO:0000250|UniProtKB:Q08004}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q08004}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q08004}. Note=Shuttles between the nucleus and
CC       the cytoplasm. {ECO:0000250|UniProtKB:Q08004}.
CC   -!- SIMILARITY: Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL132860; CAB60500.1; -; Genomic_DNA.
DR   RefSeq; NP_499552.1; NM_067151.6.
DR   AlphaFoldDB; Q9U239; -.
DR   SMR; Q9U239; -.
DR   STRING; 6239.Y56A3A.18; -.
DR   EPD; Q9U239; -.
DR   PaxDb; Q9U239; -.
DR   PeptideAtlas; Q9U239; -.
DR   EnsemblMetazoa; Y56A3A.18.1; Y56A3A.18.1; WBGene00013236.
DR   GeneID; 176624; -.
DR   KEGG; cel:CELE_Y56A3A.18; -.
DR   UCSC; Y56A3A.18; c. elegans.
DR   CTD; 176624; -.
DR   WormBase; Y56A3A.18; CE22586; WBGene00013236; -.
DR   eggNOG; KOG3408; Eukaryota.
DR   GeneTree; ENSGT00390000004173; -.
DR   HOGENOM; CLU_117291_1_2_1; -.
DR   InParanoid; Q9U239; -.
DR   OMA; TECAKWF; -.
DR   OrthoDB; 1445352at2759; -.
DR   PhylomeDB; Q9U239; -.
DR   PRO; PR:Q9U239; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00013236; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR022755; Znf_C2H2_jaz.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF12171; zf-C2H2_jaz; 1.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Metal-binding; Nucleus; Reference proteome; Ribosome biogenesis;
KW   Zinc; Zinc-finger.
FT   CHAIN           1..128
FT                   /note="Zinc finger protein 593 homolog"
FT                   /id="PRO_0000331297"
FT   ZN_FING         53..77
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   128 AA;  14570 MW;  D64476617324054A CRC64;
     MPSGGQRKHT ISNKTRKRPG KDLDQIHEDL KPEKAAKLLQ QEIDYDLPGN GQFYCIECER
     HFVDEKTRQL HRKTKLHKNR VKTLKEVPYT QAEANAAGGS GFFPAITLKT RVELPKQPEI
     PIPVVAET