ID   ZN593_DICDI             Reviewed;         141 AA.
AC   Q553S1;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Zinc finger protein 593 homolog;
GN   ORFNames=DDB_G0275351;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Involved in pre-60S ribosomal particles maturation by
CC       promoting the nuclear export of the 60S ribosome.
CC       {ECO:0000250|UniProtKB:Q08004}.
CC   -!- SUBUNIT: Associates with pre-60S ribosomal particles; released from the
CC       pre-60S particle very early in the cytoplasm.
CC       {ECO:0000250|UniProtKB:Q08004}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q08004}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q08004}. Note=Shuttles between the nucleus and
CC       the cytoplasm. {ECO:0000250|UniProtKB:Q08004}.
CC   -!- SIMILARITY: Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; AAFI02000013; EAL69741.1; -; Genomic_DNA.
DR   RefSeq; XP_643671.1; XM_638579.1.
DR   AlphaFoldDB; Q553S1; -.
DR   SMR; Q553S1; -.
DR   STRING; 44689.DDB0202563; -.
DR   PaxDb; Q553S1; -.
DR   EnsemblProtists; EAL69741; EAL69741; DDB_G0275351.
DR   GeneID; 8619937; -.
DR   KEGG; ddi:DDB_G0275351; -.
DR   dictyBase; DDB_G0275351; -.
DR   eggNOG; KOG3408; Eukaryota.
DR   HOGENOM; CLU_1731431_0_0_1; -.
DR   InParanoid; Q553S1; -.
DR   OMA; TECAKWF; -.
DR   PhylomeDB; Q553S1; -.
DR   PRO; PR:Q553S1; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR   InterPro; IPR022755; Znf_C2H2_jaz.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF12171; zf-C2H2_jaz; 1.
DR   SMART; SM00451; ZnF_U1; 1.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Metal-binding; Nucleus; Reference proteome; Ribosome biogenesis;
KW   Zinc; Zinc-finger.
FT   CHAIN           1..141
FT                   /note="Zinc finger protein 593 homolog"
FT                   /id="PRO_0000331298"
FT   ZN_FING         60..84
FT                   /note="C2H2-type"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..22
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   141 AA;  15805 MW;  7A5FC349DC09ECB8 CRC64;
     MGRYSGHGGT HTKKKQYKRA RSTKNRAKDI DQIFDEIQPE TIDKFSKFEV DPDLPGMGQN
     YCIHCSKHFV TNEDLQSHIK GKPHKIRVKE LKTKPYSLAE SQIPVDNGVK LNRDANGVPT
     TTDVTGTIKK STTTTTTTTT V