ZN665_PONAB
ID ZN665_PONAB Reviewed; 613 AA.
AC Q5R8X1;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Zinc finger protein 665;
GN Name=ZNF665;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; CR859627; CAH91789.1; -; mRNA.
DR RefSeq; NP_001126039.1; NM_001132567.2.
DR AlphaFoldDB; Q5R8X1; -.
DR SMR; Q5R8X1; -.
DR STRING; 9601.ENSPPYP00000011588; -.
DR GeneID; 100172988; -.
DR KEGG; pon:100172988; -.
DR CTD; 79788; -.
DR eggNOG; KOG1721; Eukaryota.
DR InParanoid; Q5R8X1; -.
DR OrthoDB; 1318335at2759; -.
DR Proteomes; UP000001595; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF00096; zf-C2H2; 18.
DR SMART; SM00355; ZnF_C2H2; 18.
DR SUPFAM; SSF57667; SSF57667; 10.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 18.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 18.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..613
FT /note="Zinc finger protein 665"
FT /id="PRO_0000325614"
FT ZN_FING 113..135
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 141..163
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 169..191
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 197..219
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 225..247
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 253..275
FT /note="C2H2-type 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 281..303
FT /note="C2H2-type 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 309..331
FT /note="C2H2-type 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 337..359
FT /note="C2H2-type 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 365..387
FT /note="C2H2-type 10"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 393..415
FT /note="C2H2-type 11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 421..443
FT /note="C2H2-type 12"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 449..471
FT /note="C2H2-type 13"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 477..499
FT /note="C2H2-type 14"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 505..527
FT /note="C2H2-type 15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 533..555
FT /note="C2H2-type 16"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 561..583
FT /note="C2H2-type 17"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 589..611
FT /note="C2H2-type 18"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ SEQUENCE 613 AA; 70181 MW; 95615735A95C2A51 CRC64;
MGEAFYTVKL ERLESHDTEG LSFQEVQKNT YDFECPWKDD EGNSKRVLTL QKENLPGRRD
QRDRRAAGNR LIENQLGVSF QSHLPELQQF QGEGKIYEYN QVEKSLSNRG KHYKCDECGK
VFNQNSRLTS HKRIHTGEKP YRCNECGKAF TVRSNLTIHQ VIHTGEKPYK CNECGKVFSQ
PSNLAGHQRI HTGEKPYKCN ECGKAFRAHS KLTTHQVIHT GEKPYKCNEC GKCFTQNSHL
ASHRRIHTGE KPYKCNECGK AFSVRSSLTT HQTIHTGEKP YKCNECGKVF RHNSYLTKHR
RVHTGEKPYK CNECGKAFSM HSNLTKHQII HTGEKPFKCN ECVKVFTQYS HLANHRRIHT
GEKPYRCDEC GKAFSVRSSL TTHQAIHTGE KPYKCNDCGK VFTQNSHLAS HRGIHSGEKP
YKCDECGKAF SQTSQLARHW RVHTGEKPYK CNECGKAFSV HSSLTTHQTI HTGQKPYKCN
DCGKVFRHNS YLAVHQRIHT GEKPYKCNEC GKAFSVHSNL ATHQVIHTGE KPYKCNECGK
VFTQNSHLAN HRRIHTGEKP YRCNECGKAF SVRSTLTTHM AIHTGDKPYK CNECGKVFTQ
NSNLAKHRRI HSG