CCA21_ORYSJ
ID CCA21_ORYSJ Reviewed; 490 AA.
AC Q2QQ96; A0A0P0YAB1;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Cyclin-A2-1;
DE AltName: Full=G2/mitotic-specific cyclin-A2-1;
DE Short=CycA2;1;
GN Name=CYCA2-1; OrderedLocusNames=Os12g0502300, LOC_Os12g31810;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16435118; DOI=10.1007/s00438-005-0093-5;
RA La H., Li J., Ji Z., Cheng Y., Li X., Jiang S., Venkatesh P.N.,
RA Ramachandran S.;
RT "Genome-wide analysis of cyclin family in rice (Oryza sativa L.).";
RL Mol. Genet. Genomics 275:374-386(2006).
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DP000011; ABA98639.1; -; Genomic_DNA.
DR EMBL; AP008218; BAF29847.1; -; Genomic_DNA.
DR EMBL; AP014968; BAT17261.1; -; Genomic_DNA.
DR EMBL; AK106653; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015618892.1; XM_015763406.1.
DR RefSeq; XP_015618893.1; XM_015763407.1.
DR RefSeq; XP_015618894.1; XM_015763408.1.
DR AlphaFoldDB; Q2QQ96; -.
DR SMR; Q2QQ96; -.
DR STRING; 4530.OS12T0502300-01; -.
DR PaxDb; Q2QQ96; -.
DR PRIDE; Q2QQ96; -.
DR EnsemblPlants; Os12t0502300-01; Os12t0502300-01; Os12g0502300.
DR GeneID; 4352280; -.
DR Gramene; Os12t0502300-01; Os12t0502300-01; Os12g0502300.
DR KEGG; osa:4352280; -.
DR eggNOG; KOG0654; Eukaryota.
DR HOGENOM; CLU_020695_13_3_1; -.
DR InParanoid; Q2QQ96; -.
DR OMA; ANSSKNC; -.
DR OrthoDB; 993640at2759; -.
DR Proteomes; UP000000763; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR Genevisible; Q2QQ96; OS.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Cyclin; Reference proteome.
FT CHAIN 1..490
FT /note="Cyclin-A2-1"
FT /id="PRO_0000286997"
FT REGION 34..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 122
FT /note="K -> M (in Ref. 5; AK106653)"
FT /evidence="ECO:0000305"
FT CONFLICT 177
FT /note="N -> D (in Ref. 5; AK106653)"
FT /evidence="ECO:0000305"
FT CONFLICT 251
FT /note="A -> V (in Ref. 5; AK106653)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 490 AA; 54786 MW; 2D68CD28DF87CE27 CRC64;
MAGRKENPVL TACQAPSGRI TRAQAAANRG RFGFAPSVSL PARTERKQTA KGKTKRGALD
EITSASTATS APQPKRRTVL KDVTNIGCAN SSKNCTTTSK LQQKSKPTQR VKQIPSKKQC
AKKVPKLPPP AVAGTSFVID SKSSEETQKV ELLAKAEEPT NLFENEGLLS LQNIERNRDS
NCHEAFFEAR NAMDKHELAD SKPGDSSGLG FIDIDNDNGN PQMCASYASE IYTNLMASEL
IRRPRSNYME ALQRDITKGM RGILIDWLVE VSEEYKLVPD TLYLTINLID RFLSQHYIER
QKLQLLGITS MLIASKYEEI CAPRVEEFCF ITDNTYTKAE VLKMEGLVLN DMGFHLSVPT
TKTFLRRFLR AAQASRNVPS ITLGYLANYL AELTLIDYSF LKFLPSVVAA SAVFLARWTL
DQSDIPWNHT LEHYTSYKSS DIQICVCALR ELQHNTSNCP LNAIREKYRQ QKFECVANLT
SPELGQSLFS