ZN706_CHICK
ID ZN706_CHICK Reviewed; 76 AA.
AC Q5ZMM5;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Zinc finger protein 706 {ECO:0000305};
GN Name=ZNF706 {ECO:0000250|UniProtKB:Q9Y5V0};
GN ORFNames=RCJMB04_1j21 {ECO:0000303|PubMed:15642098};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Transcription repressor involved in the exit of embryonic
CC stem cells (ESCs) from self-renewal. {ECO:0000250|UniProtKB:Q9D115}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9D115}. Nucleus
CC {ECO:0000250|UniProtKB:Q9D115}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ719359; CAG31018.1; -; mRNA.
DR RefSeq; NP_001091000.1; NM_001097531.1.
DR AlphaFoldDB; Q5ZMM5; -.
DR STRING; 9031.ENSGALP00000042800; -.
DR PaxDb; Q5ZMM5; -.
DR Ensembl; ENSGALT00000083796; ENSGALP00000063387; ENSGALG00000041200.
DR Ensembl; ENSGALT00000098913; ENSGALP00000071867; ENSGALG00000041200.
DR GeneID; 768824; -.
DR KEGG; gga:768824; -.
DR CTD; 51123; -.
DR VEuPathDB; HostDB:geneid_768824; -.
DR eggNOG; KOG4118; Eukaryota.
DR GeneTree; ENSGT00390000003465; -.
DR HOGENOM; CLU_176397_0_0_1; -.
DR InParanoid; Q5ZMM5; -.
DR OMA; EAKHPKD; -.
DR OrthoDB; 1620202at2759; -.
DR PhylomeDB; Q5ZMM5; -.
DR TreeFam; TF315171; -.
DR PRO; PR:Q5ZMM5; -.
DR Proteomes; UP000000539; Chromosome 2.
DR Bgee; ENSGALG00000041200; Expressed in ovary and 14 other tissues.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:1902455; P:negative regulation of stem cell population maintenance; ISS:UniProtKB.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR Gene3D; 4.10.1050.10; -; 1.
DR InterPro; IPR045230; MBS1/2-like.
DR InterPro; IPR007513; Uncharacterised_SERF_N.
DR InterPro; IPR026939; ZNF706/At2g23090_sf.
DR PANTHER; PTHR21213; PTHR21213; 1.
DR Pfam; PF04419; 4F5; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Metal-binding; Nucleus; Reference proteome; Repressor;
KW Translation regulation; Zinc; Zinc-finger.
FT CHAIN 1..76
FT /note="Zinc finger protein 706"
FT /id="PRO_0000047705"
FT ZN_FING 39..62
FT /note="C2H2-type"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 53..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 76 AA; 8570 MW; 3CDCABDBFDE529FF CRC64;
MARGQQKIQS QQKNAKKQAE QKKKQGHDQK AAAKAALIYT CTVCRTQMPD PKTFKQHFES
KHPKTPLPPE LADVQA
