ZN711_DANRE
ID ZN711_DANRE Reviewed; 761 AA.
AC A7Y7X5;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Zinc finger protein 711;
DE AltName: Full=Vitelline envelope protein;
GN Name=znf711; Synonyms=zvep;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND
RP SUBCELLULAR LOCATION.
RC TISSUE=Ovary;
RX PubMed=19117036; DOI=10.1002/mrd.20985;
RA Xu Y., Lei Y., Liu Q., Liu Y., Liu S., Cheng H., Deng F.;
RT "Cloning, characterization and expression of zvep, a novel vitelline
RT envelope-specific gene in the zebrafish ovary.";
RL Mol. Reprod. Dev. 76:593-600(2009).
CC -!- FUNCTION: Transcription regulator required for brain development.
CC Probably acts as a transcription factor that binds to the promoter of
CC target genes, leading to activate their expression (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm
CC {ECO:0000269|PubMed:19117036}.
CC -!- TISSUE SPECIFICITY: Present in ovary and brain but not in other tissues
CC (at protein level). {ECO:0000269|PubMed:19117036}.
CC -!- DEVELOPMENTAL STAGE: Present in ooplasm of stage I, II, and III
CC oocytes. Present in the vitelline envelope.
CC {ECO:0000269|PubMed:19117036}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; EU122381; ABV24353.1; -; mRNA.
DR RefSeq; NP_001098993.1; NM_001105523.1.
DR AlphaFoldDB; A7Y7X5; -.
DR SMR; A7Y7X5; -.
DR STRING; 7955.ENSDARP00000097432; -.
DR PaxDb; A7Y7X5; -.
DR GeneID; 562505; -.
DR KEGG; dre:562505; -.
DR CTD; 7552; -.
DR ZFIN; ZDB-GENE-081107-49; znf711.
DR eggNOG; KOG1721; Eukaryota.
DR InParanoid; A7Y7X5; -.
DR OrthoDB; 1318335at2759; -.
DR PhylomeDB; A7Y7X5; -.
DR PRO; PR:A7Y7X5; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IDA:ZFIN.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0060388; C:vitelline envelope; IDA:ZFIN.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR006794; Transcrp_activ_Zfx/Zfy-dom.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF00096; zf-C2H2; 5.
DR Pfam; PF04704; Zfx_Zfy_act; 1.
DR SMART; SM00355; ZnF_C2H2; 12.
DR SUPFAM; SSF57667; SSF57667; 6.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 1: Evidence at protein level;
KW Cytoplasm; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..761
FT /note="Zinc finger protein 711"
FT /id="PRO_0000399820"
FT ZN_FING 383..408
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 414..436
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 476..499
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 505..527
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 533..556
FT /note="C2H2-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 562..584
FT /note="C2H2-type 6; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 590..613
FT /note="C2H2-type 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 619..641
FT /note="C2H2-type 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 647..670
FT /note="C2H2-type 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 676..698
FT /note="C2H2-type 10"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 704..727
FT /note="C2H2-type 11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 733..755
FT /note="C2H2-type 12"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ SEQUENCE 761 AA; 86356 MW; E9443F25FEBC48DE CRC64;
MDQGGGILEL HKDLKMPHTM IMPDFGMSGI AHLDGEHIVV SVPEAVMVSD VVTDEEGIML
ETALEAEVVE EPDICQEDVI TTEGVIMSES ILGAEVAIQE ALSGTADLIE ETVPDQVFVA
ELMSPHIQSP LDHNLVSAEV MVTDADTVID SHDTLQSDVT IKADDDVEDV KSTSEDYLMI
SLDEVGGKLD IEDTSLKISA DVGQDDDGSK EDEFSSEVIK VYIFKADGDE DVEIGSTEVV
EESDFPGRHT VMESVGSGRL PREKMVYMAV KDANQEDDLN CSEMTDQVYM EVIVGEEEAP
AITEAQMEDS PVNKTIVPAA WATAYGSSLE SKNGAATPYL QITDSISTSR ALKQKIKKRR
RGETRQCQTA VIIGPDGQPL TVYPCHICGK KFKSRGFLKR HMKNHPDHMF KKKYQCTDCE
FTTNKKVSFH NHLESHKLII KNEKIPEYTE YTRRYHEASP LSSNKLILRD KEPKLHKCKY
CEYETAEQGL LNRHLLAVHS KNFAHVCVEC AKGFRHPSEL KKHMRTHTGE KPFHCQHCEF
SCADQSNLKT HIKSKHGTDL PFKCGHCPQA FADDKELQRH AEIFQGHKTH QCPHCEHKST
NSSDLKRHII SVHTKDFPHK CDVCEKGFHR PSELKKHSET HKGNKVHQCR HCDFKTLDPF
TLSRHILSVH TKDLPFKCKR CKRGFRHQNE LKKHMKTHSG RKVYQCQYCE YNTTDASGFK
RHVISIHTKD YPHRCDYCKK GFRRPSEKNQ HIMRHHKETL L
